Hysteroscopic metroplasty in patients with a uterine septum and otherwise unexplained infertility

Objective: To evaluate the reproductive outcomes of patients with a uterine septum and otherwise unexplained infertility who underwent hysteroscopic metroplasty, and to compare them with those of patients with the same diagnosis who did not have hysteroscopic metroplasty. Methods: The present retrospective study included 127 patients with diagnosis of a uterine septum and otherwise unexplained infertility. The reproductive outcomes of 102 patients who underwent hysteroscopic metroplasty (group 1) and 25 patients who rejected the operation (group 2) were compared. Results: Of the 102 patients who underwent hysteroscopic metroplasty, 44(43.1%) were able to achieve pregnancy, as compared with 5(20%) of the 25 patients who did not undergo the operation (P=0.03). The abortion rate was 11.4% (5/44) in group 1, compared with 60% (3/5) in group 2 (P=0.02). The live birth rate was 35.3% (36/102) in group 1, as compared with 8% (2/25) in group 2 (P=0.008). Conclusions: The results indicate that hysteroscopic metroplasty improves reproductive outcome for patients with a uterine septum and otherwise unexplained infertility. (C) 2011 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.