Current Evidence for Stereotactic Body Radiotherapy in Lung Metastases

被引：7

作者：

Gutierrez, Enrique ^{[1
,2
]}

Sanchez, Irving ^{[3
]}

Diaz, Omar ^{[3
]}

Valles, Adrian ^{[3
]}

Balderrama, Ricardo ^{[3
]}

Fuentes, Jesus ^{[3
]}

Lara, Brenda ^{[3
]}

Olimon, Cipatli ^{[3
]}

Ruiz, Victor ^{[3
]}

Rodriguez, Jose ^{[3
]}

Bayardo, Luis H. ^{[3
]}

Chan, Matthew ^{[1
,2
]}

Villafuerte, Conrad J. ^{[1
,2
]}

Padayachee, Jerusha ^{[1
,2
]}

Sun, Alexander ^{[1
,2
]}

机构：

[1] Univ Hlth Network, Princess Margaret Canc Ctr, Radiat Med Program, Toronto, ON M5G 2M9, Canada

[2] Univ Toronto, Dept Radiat Oncol, Toronto, ON M5G 2M9, Canada

[3] Mexican Inst Social Secur IMSS, Western Natl Med Ctr, Dept Radiat Oncol, Belisario Dominguez 1000, Guadalajara 44340, Jalisco, Mexico

来源：

CURRENT ONCOLOGY | 2021年 / 28卷 / 04期

关键词：

lung SBRT; oligometastatic disease; lung cancer; lung metastases; RADIATION-THERAPY SBRT; INDUCED VASCULAR DAMAGE; PULMONARY OLIGOMETASTASES; PHASE-II; COMPUTED-TOMOGRAPHY; MOTION MANAGEMENT; FDG-PET; CANCER; TRIAL; TUMORS;

D O I：

10.3390/curroncol28040233

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Lung metastases are the second most common malignant neoplasms of the lung. It is estimated that 20-54% of cancer patients have lung metastases at some point during their disease course, and at least 50% of cancer-related deaths occur at this stage. Lung metastases are widely accepted to be oligometastatic when five lesions or less occur separately in up to three organs. Stereotactic body radiation therapy (SBRT) is a noninvasive, safe, and effective treatment for metastatic lung disease in carefully selected patients. There is no current consensus on the ideal dose and fractionation for SBRT in lung metastases, and it is the subject of study in ongoing clinical trials, which examines different locations in the lung (central and peripheral). This review discusses current indications, fractionations, challenges, and technical requirements for lung SBRT.

引用

页码：2560 / 2578

页数：19

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