CONCENTRATIONS OF PERFLUORINATED COMPOUNDS IN HUMAN BLOOD FROM TWELVE CITIES IN CHINA

We detected nine perfluorinated compounds (PFCs) in 233 human whole blood samples collected from 12 cities (from 12 provinces and districts) in China Perfluorinated compounds could be detected in all blood samples with perfluorooctane sulfonate (C8 PFOS) as the most prominent PFC Mean PFOS concentrations were measured at 3 06 to 34 0 mu g/L accounting for the majority of the total perfluorinated compounds (Sigma PFCs) (54-87%) in blood samples except those from Kunming Perfluorooctane sulfonate and perfluoiohexane sulfonate (C6 PFHxS) concentrations were positively correlated in blood samples (p <0 01) Significant relations among perfluorooctanoate (C8 PFOA) perfluorononanoic acid (C9 PFNA) perfluorodecanoic acid (C10 PFDA) and perfluor oundecanoic acid (C11 PFUnDA) (p < 0 05) were also observed in the present study indicating that they may come from a similar exposure pathway in China In general gender related differences were found for PFHxS and Sigma PFCs concentrations which were significantly higher in males than in females (p < 0 05) In the 20 to 29 year age group gender influence was also found for PFHxS and PFOS concentrations The mean blood concentration of PFOS (10 6 mu g/L) in the present study was comparable with results from other countries while PFOA and PFHxS (1 39 mu g/L and 0 57 mu g/L respectively) were often lower This can probably be attributed to a different exposure pathway of the general population in China as compared to other countries Environ Toxicol Chem 2010 29 2695-2701 (C) 2010 SETAC