Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia

被引：8
|
作者：
Uijen, Iris L. [1 ,2 ]
Aaronson, Justine A. [2 ,3 ,4 ]
Karssemeijer, Esther G. A. [1 ,2 ]
Rikkert, Marcel G. M. Olde [1 ,2 ]
Kessels, Roy P. C. [2 ,4 ,5 ,6 ]
机构：
[1] Radboud Univ Nijmegen, Dept Geriatr Med, Med Ctr, Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Radboudumc Alzheimer Ctr, Med Ctr, Nijmegen, Netherlands
[3] OLVG Hosp, Amsterdam, Netherlands
[4] Radboud Univ Nijmegen, Dept Med Psychol, Med Ctr, Nijmegen, Netherlands
[5] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands
[6] Vincent van Gogh Inst Psychiat, Venray, Netherlands
来源：
JOURNAL OF ALZHEIMERS DISEASE | 2020年 / 74卷 / 02期
关键词：
APOE epsilon 4; cognitive function; dementia; physical activity; reliable change index; RISK;
D O I：
10.3233/JAD-190606
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The aim of this study was to investigate whether the effect of physical activity on cognitive function in persons with dementia is moderated by patient characteristics as Apolipoprotein E and dementia type. We included 101 individuals with dementia and calculated the reliable change index to determine the change in global cognition, executive function, episodic memory, working memory, and processing speed before and after a 12-week exercise training. We found a higher treatment-related benefit in episodic memory in persons with non-Alzheimer's disease compared to persons with Alzheimer's disease, and in executive function in individuals with better baseline cognitive function.
引用
收藏
页码：435 / 439
页数：5
相关论文
共 50 条
  • [21] Assessment of Cognitive Training & Social Interaction in People with Mild to Moderate Dementia: A Pilot Study
    Rouse, Hillary J.
    Small, Brent J.
    Faust, Mark E.
    [J]. CLINICAL GERONTOLOGIST, 2019, 42 (04) : 421 - 434
  • [22] CORRELATION BETWEEN DEPRESSION SCORE AND GLOBAL COGNITIVE SCORE IN PEOPLE WITH MILD TO MODERATE DEMENTIA
    Pradhana, I.
    Huang, F.
    Chelsea, E.
    Wiwie, M.
    [J]. INTERNATIONAL JOURNAL OF STROKE, 2022, 17 (3_SUPPL) : 267 - 267
  • [23] MANAGEMENT OF PATIENTS WITH MILD COGNITIVE IMPAIRMENT AND MILD TO MODERATE DEMENTIA
    Vandewoude, M. F. J.
    [J]. ACTA CLINICA BELGICA, 2009, 64 (02) : 92 - 99
  • [24] Physical activity and cognition in older adults with mild cognitive impairment and dementia
    Lautenschlager, Nicola T.
    [J]. NEURODEGENERATIVE DISEASE MANAGEMENT, 2013, 3 (03) : 211 - 218
  • [25] Handgrip strength, physical activity and incident mild cognitive impairment and dementia
    Werneck, Andre O.
    Araujo, Raphael H. O.
    Silva, Danilo R.
    Vancampfort, Davy
    [J]. MATURITAS, 2023, 176
  • [26] Promoting activity, independence and stability in early dementia and mild cognitive impairment (PrAISED): development of an intervention for people with mild cognitive impairment and dementia
    Booth, Vicky
    Harwood, Rowan H.
    Hood-Moore, Victoria
    Bramley, Trevor
    Hancox, Jennie E.
    Robertson, Kate
    Hall, Judith
    Van der Wardt, Veronika
    Logan, Pip A.
    [J]. CLINICAL REHABILITATION, 2018, 32 (07) : 855 - 864
  • [27] Omega-3 fatty acids moderate effects of physical activity on cognitive function
    Leckie, Regina L.
    Manuck, Stephen B.
    Bhattacharjee, Neha
    Muldoon, Matthew F.
    Flory, Janine M.
    Erickson, Kirk I.
    [J]. NEUROPSYCHOLOGIA, 2014, 59 : 103 - 111
  • [28] The Usability of Physical Activity and Cognitive Training Applications in People With Mild Cognitive Impairment
    Smith, Lenora
    Argentina, Vinny
    [J]. RESEARCH IN GERONTOLOGICAL NURSING, 2020, 13 (02) : 64 - 72
  • [29] Is there a role for physical activity in preventing cognitive decline in people with mild cognitive impairment?
    Barber, Sally E.
    Clegg, Andrew P.
    Young, John B.
    [J]. AGE AND AGEING, 2012, 41 (01) : 5 - 8
  • [30] Development of an exercise intervention to improve cognition in people with mild to moderate dementia: Dementia And Physical Activity (DAPA) Trial, registration ISRCTN32612072
    Brown, Deborah
    Spanjers, Katie
    Atherton, Nicky
    Lowe, Janet
    Stonehewer, Louisa
    Bridle, Chris
    Sheehan, Bart
    Lamb, Sarah E.
    [J]. PHYSIOTHERAPY, 2015, 101 (02) : 126 - 134
12345