Ultrasonic-assisted-synthesis of isoindolin-1-one derivatives

被引：10

作者：

Mardjan, Muhammad Idham Darussalam ^{[1
]}

Hariadi, Muhamad Fadhly ^{[1
]}

Putri, Indah Mutiara ^{[1
]}

Musyarrofah, Nilna Amalia ^{[1
]}

Salimah, Muflihah ^{[1
]}

Purwono, Bambang ^{[1
]}

Commeiras, Laurent ^{[2
]}

机构：

[1] Univ Gadjah Mada, Fac Math & Nat Sci, Dept Chem, Bulaksumur POS BLS 21, Yogyakarta 55281, Indonesia

[2] Aix Marseille Univ, iSm2, Cent Marseille, CNRS, F-13013 Marseille, France

来源：

RSC ADVANCES | 2022年 / 12卷 / 29期

关键词：

N-ACYL KETIMINES; MULTICOMPONENT REACTION; STRAIGHTFORWARD ACCESS; 3+2 ANNULATION; SONOCHEMISTRY; CHEMISTRY; ALDEHYDES; LACTAMS;

D O I：

10.1039/d2ra02720h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A small library of 3-hydroxyisoindolin-1-ones has been prepared from 3-alkylidenephtalides under ultrasonic irradiation. This practical synthesis is featured by group tolerance, high efficiency and yields. The reaction can also be performed in multigram scale and be further extended to access other motifs of isoindolin-1-ones in a one-pot fashion.

引用

页码：19016 / 19021

页数：6

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