Efficient copper(II)-catalyzed addition of activated methylene compounds to alkenes

被引：51
|
作者：
Li, Yu [1 ]
Yu, Zhengkun [1 ,2 ]
Wu, Sizhong [1 ]
机构：
[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 73卷 / 14期
关键词：
D O I：
10.1021/jo800836g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Efficient regioselective addition of beta-diketones to styrenes, norbornene, cyclic enol ether, and diene has been realized by means of copper(II) triflate as the catalyst. The solvent effect is prominent on the reactions, and the desired addition products were obtained in good to excellent yields only in dioxane or ionic liquid [bmim]PF6. The mechanism suggests that copper(II) triflate activates the enolic O-H bond of a beta-diketone substrate to initiate the addition reaction.
引用
收藏
页码：5647 / 5650
页数：4
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