Chronic infection of Balb/c mice with murine herpesvirus 72 is associated with neoplasm development

被引：0
|
作者：
Mistrikova, J [1 ]
Rajcani, J [1 ]
Mrmusova, M [1 ]
Oravcova, I [1 ]
机构：
[1] SLOVAK ACAD SCI,INST VIROL,BRATISLAVA,SLOVAKIA
来源：
ACTA VIROLOGICA | 1996年 / 40卷 / 5-6期
关键词：
murine herpes virus; neoplasm; tumour; lymphoproliferative disease;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
One hundred Balb/c mice were infected with murine herpesvirus strain 72 (MHV-72) and observed for 2.5 years for neoplasm development and virus presence in tumour as well as non-tumour tissues. Out of 13 neoplasm-bearing mice the virus was recovered from solid tumours (one lymphoma, two nondifferentiated lymphoblastomas and two fibrosarcomas) of five mice and from the spleen of one mouse with lymphatic leukemia. The virus persisted frequently also in various organs of the neoplasm-bearing mice.
引用
收藏
页码：297 / 301
页数：5
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