The CD34 molecule and hematopoietic progenitor cell studies - a challenge in clinical medicine

被引:3
|
作者
Egeland, T [1 ]
机构
[1] Univ Oslo, Natl Hosp, Rikshosp, Inst Transplantat Immunol, N-0027 Oslo, Norway
关键词
D O I
10.1111/j.1423-0410.1998.tb05458.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The CD34 molecule, which is expressed at various levels on virtually all human hematopoietic progenitor cells (HPC), is a heavy glycosylated molecule with many different epitopes. A large series of CD34-specific monoclonal antibodies specific for different epitopes has been generated. Some of these antibodies do not react with particular HPC subpopulations. Thus, the antibodies used for HPC enumeration and isolation have to be carefully chosen with respect to what is aimed at.
引用
收藏
页码:467 / 468
页数:2
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