Three new anthraquinones from the twigs of Cassia auriculata Linn. and their antibacterial activity

被引:9
|
作者
Yang, Feng-Xian [1 ]
Mi, Qi-Li [1 ]
Zhu, Ya-Ning
Shi, Jian-Quan [1 ]
Zhou, Tao [1 ,2 ,3 ]
Zhang, Jian-Duo [1 ]
Xiang, Hai-Ying [1 ]
Zeng, Wan-Li [1 ]
Yang, Guang-Yu [1 ,2 ,3 ]
Zhou, Min [2 ,3 ]
Hu, Qiu-Fen [2 ,3 ]
Yin, Geng-Yun [1 ]
机构
[1] China Tobacco Yunnan Ind Co Ltd, Technol Ctr, Kunming 650231, Peoples R China
[2] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Peoples R China
[3] Yunnan Minzu Univ, Minist Educ, Kunming 650031, Peoples R China
关键词
Anthraquinones; Anti-MRSA activity; Cassia auriculata Linn; CONSTITUENTS; EXTRACT;
D O I
10.1016/j.phytol.2021.06.011
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new anthraquinones (1-3), together with four known analogues (4-7) were isolated from the twigs of Cassia auriculata Linn.. Their structures were elucidated by extensive spectroscopic analysis and comparison of spectroscopic data with those reported in literatures. All compounds were tested for their anti-methicillinresistant Staphylococcus aureus (anti-MRSA) activity. Compounds 1, 2 and 7 showed modest antibacterial activity against MRSA with MIC values of 4.2, 5.0, 4.7 mu g/mL, and compounds 3, 4, 5 and 6 showed weak antibacterial activity against MRSA with MIC valves of 9.2, 7.6, 7.1, 9.6 mu g/mL, respectively.
引用
收藏
页码:125 / 128
页数:4
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