Learning transmission dynamics modelling of COVID-19 using comomodels

被引:3
|
作者
van der Vegt, Solveig A. [1 ,2 ]
Dai, Liangti [1 ,3 ]
Bouros, Loana [1 ,4 ]
Farm, Hui Jia [4 ]
Creswell, Richard [4 ]
Dimdore-Miles, Oscar [7 ]
Cazimoglu, Idil [1 ]
Bajaj, Sumali [1 ]
Hopkins, Lyle [1 ,4 ]
Seiferth, David [1 ]
Cooper, Fergus [1 ,4 ]
Lei, Chon Lok [5 ,6 ]
Gavaghan, David [1 ,4 ]
Lambert, Ben [1 ,8 ]
机构
[1] Univ Oxford, Doctoral Training Ctr, Oxford, England
[2] Univ Oxford, Math Inst, Wolfson Ctr Math Biol, Oxford, England
[3] Univ Oxford, MRC Weatherall Inst Mol Med, MRC WIMM Ctr Computat Biol, Oxford, England
[4] Univ Oxford, Dept Comp Sci, Oxford, England
[5] Univ Macau, Inst Translat Med, Fac Hlth Sci, Zhuhai, Macao, Peoples R China
[6] Univ Macau, Fac Hlth Sci, Dept Biomed Sci, Zhuhai, Macao, Peoples R China
[7] Univ Oxford, Ocean & Planetary Phys Dept, Atmospher, Oxford, England
[8] Univ Exeter, Coll Engn Math & Phys Sci, Dept Math, Exeter, England
关键词
Epidemiology; COVID-19; Population dynamics; Pedagogy; Compartmental models; Infectious disease modelling;
D O I
10.1016/j.mbs.2022.108824
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The COVID-19 epidemic continues to rage in many parts of the world. In the UK alone, an array of mathematical models have played a prominent role in guiding policymaking. Whilst considerable pedagogical material exists for understanding the basics of transmission dynamics modelling, there is a substantial gap between the relatively simple models used for exposition of the theory and those used in practice to model the transmission dynamics of COVID-19. Understanding these models requires considerable prerequisite knowledge and presents challenges to those new to the field of epidemiological modelling. In this paper, we introduce an open-source R package, comomodels, which can be used to understand the complexities of modelling the transmission dynamics of COVID-19 through a series of differential equation models. Alongside the base package, we describe a host of learning resources, including detailed tutorials and an interactive web-based interface allowing dynamic investigation of the model properties. We then use comomodels to illustrate three key lessons in the transmission of COVID-19 within R Markdown vignettes.
引用
收藏
页数:11
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