The outbreak of COVID-19 caused by SARS-CoV-2 in Wuhan and other cities in China in 2019 has become a global pandemic as declared by the World Health Organization (WHO) in the first quarter of 2020. The delay in diagnosis, limited hospital resources and other treatment resources led to the rapid spread of COVID-19. Optimal control dynamical models with time-dependent functions are very powerful mathematical modeling tools to investigate the transmission of infectious diseases. In this study, we have introduced and studied a new mathematical model for COVID-19 disease using personal protection, hospitalization and treatment of infectious individuals with early diagnosis, hospitalization and treatment of infectious individuals with delayed diagnosis and spraying of the environment as time-dependent control functions. This new non-autonomous deterministic epidemic model for the 2019 coronavirus disease is an extension of a recently constructed and analyzed datadriven non-optimal control model. We investigated three control strategies for our model problem. From the numerical illustrations of the various control strategies, we realized that the third strategy, which captures all the four time-dependent control functions, yields better results.
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Carleton Univ, Sch Math & Stat, Ottawa, ON K1S 5B6, Canada
Univ Teknol Malaysia, Dept Math Sci, Johor Baharu 81310, MalaysiaCarleton Univ, Sch Math & Stat, Ottawa, ON K1S 5B6, Canada
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Islamic Azad Univ, Fac Sci, Dept Math, Tabriz Branch, Tabriz, IranCarleton Univ, Sch Math & Stat, Ottawa, ON K1S 5B6, Canada
Chaharborj, Shahriar Seddighi
Phang, Pei See
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Univ Putra Malaysia, Fac Sci, Dept Math, Seri Kembangan 43400, Selangor, Malaysia
Brilliant Student Care 838, Jurong West St 81, Singapore 640838, SingaporeCarleton Univ, Sch Math & Stat, Ottawa, ON K1S 5B6, Canada
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Univ Cambridge, Sch Clin Med, Med Res Council, Biostat Unit, Cambridge, EnglandUniv Cambridge, Sch Clin Med, Med Res Council, Biostat Unit, Cambridge, England
Liu, Yang
Tang, Julian W.
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Univ Leicester, Resp Sci, Leicester, Leics, EnglandUniv Cambridge, Sch Clin Med, Med Res Council, Biostat Unit, Cambridge, England
Tang, Julian W.
Lam, Tommy T. Y.
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Univ Hong Kong, Sch Publ Hlth, State Key Lab Emerging Infect Dis, Hong Kong, Peoples R ChinaUniv Cambridge, Sch Clin Med, Med Res Council, Biostat Unit, Cambridge, England
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Boston Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
Boston Univ, Sch Publ Hlth, Dept Global Hlth, Boston, MA USAAteneo Manila Univ, Sch Sci & Engn, Hlth Sci Program, Quezon City, Philippines
Sy, K. T. L.
Abrigo, M. R. M.
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Philippine Inst Dev Studies, Makati, PhilippinesAteneo Manila Univ, Sch Sci & Engn, Hlth Sci Program, Quezon City, Philippines