Graphene-based biosensors for dopamine determination

被引：10
|
作者：
Fritea, Luminita [1 ,2 ]
Tertis, Mihaela [1 ]
Le Goff, Alan [2 ]
Cosnier, Serge [2 ]
Sandulescu, Robert [1 ]
Cristea, Cecilia [1 ]
机构：
[1] Iuliu Ha Ieganu Univ Med & Pharm, Analyt Chem Dept, 4 Pasteur St, Cluj Napoca 400349, Romania
[2] Univ Joseph Fourier, Dept Chim Mol UMR 5250, ICMG FR 2607, CNRS, BP 53, F-38041 Grenoble, France
来源：
BIOSENSORS 2016 | 2017年 / 27卷
关键词：
graphene; -cyclodextrin; polypyrrole; biosensor; dopamine;
D O I：
10.1016/j.protcy.2017.04.046
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Two different graphene/ -cyclodextrin (CD)-based biosensors were elaborated for dopamine (DA) determination starting from glassy carbon electrode (GCE). First one was obtained by modifying GCE with reduced graphene oxide (RGO), CD and tyrosinase (Tyr) immobilized with a polyethylenimine film. The second biosensor was obtained after the incorporation of RGO functionalized with a new synthesized pyrrole- -CD derivative and Tyr in an electropolimerized poly-amphiphilic pyrrole film. These two new approaches have resulted in selective and sensitive determination of DA in pharmaceuticals and real human samples. (C) 2017 The Authors. Published by Elsevier Ltd.
引用
收藏
页码：106 / 107
页数：2
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