Graphene-Based Biosensors

被引:11
|
作者
Lebedev, A. A. [1 ,2 ]
Davydov, V. Yu. [1 ]
Novikov, S. N. [3 ]
Litvin, D. P. [1 ,4 ]
Makarov, Yu. N. [4 ,5 ]
Klimovich, V. B. [6 ]
Samoilovich, M. P. [6 ,7 ]
机构
[1] Russian Acad Sci, Ioffe Phys Tech Inst, St Petersburg 194021, Russia
[2] St Petersburg Natl Univ Informat Technol Mech & O, St Petersburg 197101, Russia
[3] Aalto Univ, Tietotie 3, Espoo 02150, Finland
[4] Nitridnye Kristally Grp, St Petersburg 194156, Russia
[5] Nitride Crystals Inc, Deer Pk, NY 11729 USA
[6] Minist Publ Hlth Russian Federat, Russian Sci Ctr Radiol & Surg Technol, St Petersburg 197758, Russia
[7] St Petersburg State Univ, St Petersburg 199034, Russia
关键词
D O I
10.1134/S1063785016070233
中图分类号
O59 [应用物理学];
学科分类号
摘要
Results of developing and testing graphene-based sensors capable of detecting protein molecules are presented. The biosensor operation was checked using an immunochemical system comprising fluorescein dye and monoclonal antifluorescein antibodies. The sensor detects fluorescein concentration on a level of 1-10 ng/mL and bovine serum albumin-fluorescein conjugate on a level of 1-5 ng/mL. The proposed device has good prospects for use for early diagnostics of various diseases.
引用
收藏
页码:729 / 732
页数:4
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