The development of retinal microglia was studied during embryonic (E) and postnatal (P) stages using various markers (Iba-1, F4/80, anti-CD68, anti-CD45 and tomato lectin) that recognize different forms of macrophage/microglial cells. Labeled cells were already present in the retina at El 1.5 and increased in number during subsequent embryo development. A marked decrease in microglial density was observed immediately after birth, but the density of microglial cells again increased during the first postnatal week.
机构:
Univ Calif San Francisco, Sch Med, Dept Ophthalmol, San Francisco, CA 94143 USAUniv Calif San Francisco, Sch Med, Dept Ophthalmol, San Francisco, CA 94143 USA
Copenhagen, DR
Tian, N
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Univ Calif San Francisco, Sch Med, Dept Ophthalmol, San Francisco, CA 94143 USAUniv Calif San Francisco, Sch Med, Dept Ophthalmol, San Francisco, CA 94143 USA
机构:
Eye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual ScienceEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Bilin Rao
Xiaoqing Liu
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Wenzhou Medical University,Laboratory of Retinal Physiology and Disease, School of Ophthalmology and Optometry and Eye HospitalEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Xiaoqing Liu
Jiayi Xiao
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Wenzhou Medical University,Laboratory of Retinal Physiology and Disease, School of Ophthalmology and Optometry and Eye HospitalEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Jiayi Xiao
Xiaotian Wu
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Wenzhou Medical University,Laboratory of Retinal Physiology and Disease, School of Ophthalmology and Optometry and Eye HospitalEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Xiaotian Wu
Fang He
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Wenzhou Medical University,Laboratory of Retinal Physiology and Disease, School of Ophthalmology and Optometry and Eye HospitalEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Fang He
Qingwen Yang
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Wenzhou Medical University,Laboratory of Retinal Physiology and Disease, School of Ophthalmology and Optometry and Eye HospitalEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Qingwen Yang
Wenna Zhao
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Wenzhou Medical University,Laboratory of Retinal Physiology and Disease, School of Ophthalmology and Optometry and Eye HospitalEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Wenna Zhao
Xin Lin
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Wenzhou Medical University,Laboratory of Retinal Physiology and Disease, School of Ophthalmology and Optometry and Eye HospitalEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science
Xin Lin
Jun Zhang
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Eye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual ScienceEye Hospital,State Key Laboratory of Ophthalmology, Optometry and Visual Science