Inhibition of hepatitis B virus X protein in HBV-infected primary human hepatocytes leads to the reappearance of the Smc5/6 complex

被引:0
|
作者
Beran, R. [1 ]
Voitenleitner, C. [1 ]
Kornyeyev, D. [1 ]
Livingston, C. [1 ]
Xing, W. [1 ]
Kwon, H. [1 ]
Fletcher, S. [1 ]
机构
[1] Gilead Sci, Biol, Foster City, CA USA
关键词
D O I
10.1016/S0168-8278(18)31811-7
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
SAT-366
引用
收藏
页码:S772 / S773
页数:2
相关论文
共 50 条
  • [31] The C-terminal region of the hepatitis B virus X protein is required for its stimulation of HBV replication in primary mouse hepatocytes
    Luo, Na
    Cai, Yuan
    Zhang, Jun
    Tang, Weixue
    Slagle, Betty L.
    Wu, Xiaoling
    He, Song
    VIRUS RESEARCH, 2012, 165 (02) : 170 - 178
  • [32] Central role of the hepatitis B virus X protein for the initiation of infection in primary hepatocytes.
    Köck, J
    Baumert, TF
    Protzer, U
    Blum, HE
    von Weizsäcker, F
    HEPATOLOGY, 2003, 38 (04) : 612A - 612A
  • [33] Relationship of human leukocyte antigen class II genes with the susceptibility to hepatitis B virus infection and the response to interferon in HBV-infected patients
    Han, Yong-Nian
    Yang, Jin-Long
    Zheng, Shui-Gen
    Tang, Qun
    Zhu, Wei
    WORLD JOURNAL OF GASTROENTEROLOGY, 2005, 11 (36) : 5721 - 5724
  • [35] The Hepatitis B Virus X Gene is Transcribed Very Early after Infection of Primary Human Hepatocytes and Prior to Expression of the Other HBV Genes
    Beran, Rudolf K.
    Livingston, Christine M.
    Li, Li
    Niu, Congrong
    Burdette, Dara
    Daffis, Stephane
    Cheng, Guofeng
    Yu, Mei
    Delaney, William E.
    Fletcher, Simon P.
    HEPATOLOGY, 2016, 64 : 298A - 298A
  • [36] RPB5-Mediating Protein Suppresses Hepatitis B Virus (HBV) Transcription and Replication by Counteracting the Transcriptional Activation of Hepatitis B virus X Protein in HBV Replication Mouse Model
    Zhou, Qiaoling
    Huang, Feijun
    Chen, Lanlan
    Chen, Enqiang
    Bai, Lang
    Cheng, Xing
    He, Min
    Tang, Hong
    JUNDISHAPUR JOURNAL OF MICROBIOLOGY, 2015, 8 (09)
  • [37] Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus
    Berke, Jan Martin
    Dehertogh, Pascale
    Vergauwen, Karen
    Van Damme, Ellen
    Mostmans, Wendy
    Vandyck, Koen
    Pauwels, Frederik
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2017, 61 (08)
  • [38] Enhanced angiopoietin-2 expression in liver tissue of hepatitis B virus (HBV) infected patients is mediated by HBV X protein (HBx)
    Sanz-Cameno, P.
    Martin-Vilchez, S.
    Borque, M. J.
    Moreno-Monteagudo, J. A.
    Lopez-Cabrera, M.
    Moreno-Otero, R.
    JOURNAL OF HEPATOLOGY, 2006, 44 : S150 - S150
  • [39] The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes
    Gearhart, Tricia L.
    Bouchard, Michael J.
    VIRUS RESEARCH, 2011, 155 (01) : 363 - 367
  • [40] Hepatitis V virus (HBV) cccDNA mini-chromosome transposaseaccessible chromatin by atac-sec in infected primary human hepatocytes (PHHs)
    Floriot, Oceane
    Alfano, Vincenzo
    Pascucci, Giuseppe Rubens
    Pallocca, Matteo
    De Nicola, Francesca
    Michel, Rivoire
    Plissonnier, Marie-Laure
    Zeisel, Mirjam
    Levrero, Massimo
    Guerrieri, Francesca
    JOURNAL OF HEPATOLOGY, 2020, 73 : S850 - S850