The Tandem Claisen Rearrangement in Organic Synthesis

被引：3
|
作者：
Zhang, Xueqin [1 ]
Huang, Gangliang [1 ]
Huang, Siqi [1 ]
机构：
[1] Chongqing Normal Univ, Act Carbohydrate Res Ctr, Chongqing 401331, Peoples R China
来源：
CURRENT ORGANIC CHEMISTRY | 2017年 / 21卷 / 27期
关键词：
Tandem Claisen rearrangement; variants; organic synthesis; reaction step; efficiency; application; CYCLIZATION/CLAISEN REARRANGEMENT; ALDER/CLAISEN REARRANGEMENT; CONSTRUCTION; METATHESIS; SEQUENCE; DESYMMETRIZATION; DESIGN; ROUTE; CORE;
D O I：
10.2174/1385272821666170927162859
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Background: Claisen rearrangement is an important reaction, and some "variants" are brought out under the inspiration of Claisen reaction, e.g. Bellus-Claisen rearrangement, Eschenmoser-Claisen rearrangement, Ireland-Claisen rearrangement, and Johnson-Claisen rearrangement. Objective: The application of tandem Claisen rearrangement in organic synthesis was analyzed and discussed herein. Method: We chose some important synthetic studies utilizing the tandem Claisen rearrangement as the key transformation and concisely described and discussed their contents. Results: The tandem reaction could shorten the reaction steps and improve the reaction yield. Conclusion: So, the tandem Claisen rearrangement would greatly improve the efficiency of reaction.
引用
收藏
页码：2776 / 2782
页数：7
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