Thermally responsive polymer-nanoparticle composites for biomedical applications

被引：82
|
作者：
Strong, Laura E. [1 ]
West, Jennifer L. [1 ]
机构：
[1] Rice Univ, Dept Bioengn, Houston, TX 77251 USA
来源：
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY | 2011年 / 3卷 / 03期
关键词：
MAGNETIC HYDROGEL NANOCOMPOSITES; GOLD NANOPARTICLES; DRUG-DELIVERY; N-ISOPROPYLACRYLAMIDE; REVERSIBLE ADDITION; OXIDE NANOPARTICLES; SENSITIVE HYDROGELS; OPTICAL-PROPERTIES; TEMPERATURE; POLY(N-ISOPROPYLACRYLAMIDE);
D O I：
10.1002/wnan.138
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Thermally responsive polymer-metal nanoparticle composites couple the ability of certain metal nanoparticles to convert external stimuli to heat with polymers that display sharp property changes in response to temperature changes, allowing for external control over polymer properties. These systems have been investigated for a variety of biomedical applications, including drug delivery, microfluidic valve control, and cancer therapy. This article focuses on three different size scales of this system: bulk systems (> 1 mm), nano-or microscale systems, and individual particle coatings. These composite systems will continue to be widely researched in the future for their vast potential in various biomedical applications. (C) 2011 John Wiley & Sons, Inc. WIREs Nanomed Nanobiotechnol 2011 3 307-317 DOI:10.1002/wnan.138
引用
收藏
页码：307 / 317
页数：11
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