Development of a novel molecular model and the rationalisation of a series of novel inhibitors of 17a-hydroxylase/17,20-Iyase

被引：0
|
作者：
Acharya, P. [1 ]
Shahid, I. [1 ]
Owen, C. P. [1 ]
Ahmed, S. [1 ]
机构：
[1] Univ W Scotland, Sch Sci, Paisley, Renfrew, Scotland
来源：
JOURNAL OF PHARMACY AND PHARMACOLOGY | 2010年 / 62卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1368 / 1368
页数：1
相关论文
共 50 条
  • [1] The broad phenotypic spectrum of 17α-hydroxylase/17,20-Iyase (CYP17A1) deficiency: a case series
    Sun, Min
    Mueller, Jonathan W.
    Gilligan, Lorna C.
    Taylor, Angela E.
    Shaheen, Fozia
    Noczynska, Anna
    T'Sjoen, Guy
    Denvir, Louise
    Shenoy, Savitha
    Fulton, Piers
    Cheetham, Timothy D.
    Gleeson, Helena
    Rahman, Mushtaqur
    Krone, Nils P.
    Taylor, Norman F.
    Shackleton, Cedric H. L.
    Arlt, Wiebke
    Idkowiak, Jan
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2021, 185 (05) : 729 - 741
  • [2] Two cases of 17α-hydroxylase/17,20-Iyase deficiency caused by the CYP17A1 mutation
    Lee, Hae In
    Kwon, Ahreum
    Suh, Jung Hwan
    Choi, Han Saem
    Song, Kyung Chul
    Chae, Hyun Wook
    Kim, Ho-Seong
    ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2021, 26 (01) : 66 - 70
  • [3] Novel CYP17A1 mutation in a Japanese patient with combined 17a-hydroxylase/17,20-lyase deficiency
    Katsumata, Noriyuki
    Ogawa, Eishin
    Fujiwara, Ikuma
    Fujikura, Kaori
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2010, 59 (02): : 275 - 278
  • [4] A novel molecular modelling study of inhibitors of the 17α-hydroxylase component of the enzyme system 17α-hydroxylase/17,20-lyase (P-45017α)
    Ahmed, S
    BIOORGANIC & MEDICINAL CHEMISTRY, 1999, 7 (08) : 1487 - 1496
  • [5] Modeling study of some inhibitors of 17,20-lyase, a component of the enzyme 17α-hydroxylase/17,20-lyase:: A novel approach
    Ahmed, S
    Keane, J
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 253 (02) : 273 - 276
  • [6] Novel mutations of the CYP17A1 gene in four Chinese 46,XX cases with partial 17a-hydroxylase/17,20-lyase deficiency
    Xia, Yanjie
    Shi, Panlai
    Xia, Junke
    Zhang, Huijuan
    Xu, Lijun
    Kong, Xiangdong
    STEROIDS, 2021, 173
  • [7] Molecular study of five Chinese patients with 46XX partial 17a-hydroxylase/17,20-lyase deficiency
    Tian, Qinjie
    Yao, Fengxia
    Zhang, Yiwen
    Tseng, Hung
    Lang, Jinghe
    GYNECOLOGICAL ENDOCRINOLOGY, 2012, 28 (03) : 234 - 238
  • [8] Novel inhibitors of the enzyme complex 17α-hydroxylase (17α-OHase) and 17,20-lyase based on a phenyl acyl azole backbone
    Lee, W. -Y.
    Shahid, I.
    Owen, C. P.
    Ahmed, S.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2008, 60 : A53 - A53
  • [9] Two novel mutations found in a patient with 17A-hydroxylase enzyme deficiency
    Ergun-Longmire, B
    New, MI
    Wilson, RC
    AMERICAN JOURNAL OF HYPERTENSION, 2004, 17 (05) : 154A - 154A
  • [10] Stereoselective synthesis of some 17β-dihydrooxazinyl steroids, as novel presumed inhibitors of 17α-hydroxylase-C17,20-lyase
    Wolfling, Janos
    Oravecz, Eva Andrea
    Ondre, Dora
    Mernyak, Erzsebet
    Schneider, Gyula
    Toth, Istvan
    Szecsi, Mihaly
    Julesz, Janos
    STEROIDS, 2006, 71 (09) : 809 - 816
12345