Integrated optofluidic label-free biosensors using a silicon-nitride-based coupled-resonator optical waveguide

被引：4
|
作者：
Wang, Jiawei [1 ]
Yao, Zhanshi [1 ]
Poon, Andrew W. [1 ]
机构：
[1] Hong Kong Univ Sci & Technol, Photon Device Lab, Dept Elect & Comp Engn, Hong Kong, Hong Kong, Peoples R China
来源：
INTEGRATED OPTICS: DEVICES, MATERIALS, AND TECHNOLOGIES XX | 2016年 / 9750卷
关键词：
Label-free biosensors; silicon nitride; integrated optofluidics; coupled-resonator optical waveguide (CROW); microring resonators; CMOS-compatible; elastic light scattering; visible wavelengths; SENSORS;
D O I：
10.1117/12.2214100
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
In this paper, we report our recent progress in silicon-nitride-based optofluidic label-free biosensors using a surface-functionalized coupled-resonator optical waveguide (CROW) in the visible wavelengths. The working principle is based on far-field imaging of the CROW mode-field intensity distributions at a fixed probe wavelength. The imaged pattern variation reflects real-time analyte-binding information on the CROW surfaces. Our surface-functionalized 16-microring CROW reveals six eigenstates with distinctive mode-field intensity distributions. Our proof-of-concept sensing experiment at an arbitrarily chosen probe wavelength within the CROW transmission band shows a detection of streptavidin concentration down to 40 ng/ml.
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页数：10
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