Coordination polymer particles as potential drug delivery systems

被引：211
|
作者：
Imaz, Inhar [1 ]
Rubio-Martinez, Marta [1 ]
Garcia-Fernandez, Lorena [1 ]
Garcia, Francisca [2 ]
Ruiz-Molina, Daniel [1 ]
Hernando, Jordi [3 ]
Puntes, Victor [1 ]
Maspoch, Daniel [1 ]
机构：
[1] Ctr Invest Nanociencia & Nanotecnol ICN CSIC, Bellaterra 08193, Spain
[2] Univ Autonoma Barcelona, Dept Quim, Bellaterra 08193, Spain
[3] Inst Biotecnol & Biomed, Bellaterra 08193, Spain
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 26期
关键词：
METAL-ORGANIC FRAMEWORKS; COLLOIDAL PARTICLES; SUBMICROMETER-SCALE; HYBRID MATERIALS; NANOPARTICLES; RELEASE; MODEL; MICROPARTICLES;
D O I：
10.1039/c003084h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Micro- and nanoscale coordination polymer particles can be used for encapsulating and delivering drugs. In vitro cancer cell cytotoxicity assays showed that these capsules readily release doxorubicin, which shows anticancer efficacy. The results from this work open up new avenues for metal-organic capsules to be used as potential drug delivery systems.
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页码：4737 / 4739
页数：3
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