Design and synthesis of novel artemisinin hybrids with potent activities against human colorectal cancer cells in vitro and in vivo (vol 182, 111665, 2019)

被引:1
|
作者
Wang, Liang-Liang [1 ,2 ,3 ]
Kong, Lingmei [1 ,2 ,3 ]
Liu, Hui [4 ]
Zhang, Yunqin [1 ,2 ,3 ]
Zhang, Li [4 ]
Liu, Xingyong [4 ]
Yuan, Feng [1 ,2 ,3 ]
Li, Yan [1 ,2 ,3 ]
Zuo, Zhili [1 ,2 ,3 ,4 ]
机构
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
[2] Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[4] Sichuan Univ Sci & Engn, Sch Chem Engn, Zigong, Peoples R China
关键词
D O I
10.1016/j.ejmech.2020.112256
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models
    Han, M. Ihsan
    Atalay, Pinar
    Tunc, Cansu Umran
    Unal, Gokhan
    Dayan, Serkan
    Aydin, Omer
    Kucukguzel, S. Guniz
    BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 37
  • [32] Novel isatin derivatives of podophyllotoxin: synthesis and cytotoxic evaluation against human leukaemia cancer cells as potent anti-MDR agents
    Zhang, Lei
    Chen, Fan
    Wang, Jing
    Chen, Yongzheng
    Zhang, Zeguo
    Lin, Ya
    Zhu, Xinling
    RSC ADVANCES, 2015, 5 (118): : 97816 - 97823
  • [33] Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities
    Xi, Jian-Bei
    Fang, Yan-Fen
    Frett, Brendan
    Zhu, Meng-Li
    Zhu, Tong
    Kong, Yan-Nan
    Guan, Feng-Jie
    Zhao, Yun
    Zhang, Xiong-Wen
    Li, Hong-Yu
    Ma, Ming-Liang
    Hu, Wenhao
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 126 : 1083 - 1106
  • [34] In Vitro and In Vivo Effects of Synthesis Novel Phenoxyacetamide Derivatives as Potent Apoptotic Inducer against HepG2 Cells through PARP-1 Inhibition
    Sayed, Mai M.
    Nabil, Zohour I.
    El-Shenawy, Nahla S.
    Al-Eisa, Rasha A.
    Nafie, Mohamed S.
    PHARMACEUTICALS, 2023, 16 (11)
  • [35] Design and Synthesis of Unsymmetric Benzils, Quinoxalines, and Evaluations of their Anticancer Activities against Human Non-Small Lung Cancer Cells
    Hsu, Ping-Chih
    Hsu, Yu-Hsin
    Chang, Chuan-Hsin
    Shih, Tzenge-Lien
    CHEMMEDCHEM, 2025, 20 (06)
  • [36] Synthesis and Anti-tumor Activities of Novel Phenyl Substituted Suberoylanilide Hydroxamic Acid Derivatives Against Human Cancer Cells
    Xie, Rui
    Shi, Jinghua
    Qu, Yue
    Tang, Pingwah
    Wu, Xinying
    Yang, Ming
    Yuan, Qipeng
    MEDICINAL CHEMISTRY, 2015, 11 (07) : 636 - 648
  • [37] A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments
    Hefny, Salma M.
    El-Moselhy, Tarek F.
    El -Din, Nabaweya
    Ammara, Andrea
    Angeli, Andrea
    Ferraroni, Marta
    El-Dessouki, Ahmed M.
    Shaldam, Moataz A.
    Yahya, Galal
    Al-Karmalawy, Ahmed A.
    Supuran, Claudiu T.
    Tawfik, Haytham O.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 274
  • [38] Design, Synthesis, and In Vitro/In Vivo Anti-Cancer Activities of Novel (20S)-10,11-Methylenedioxy-Camptothecin Heterocyclic Derivatives
    Dai, Xiufen
    Wu, Guanzhao
    Zhang, Yixuan
    Zhang, Xiaomin
    Yin, Ruijuan
    Qi, Xin
    Li, Jing
    Jiang, Tao
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (22) : 1 - 19
  • [39] Antibody-drug conjugates (ADCs) with a novel DNA-alkylating agent, DGN462, are highly potent in vitro and in vivo against human cancer models
    Whiteman, Kathleen
    Audette, Charlene
    Dandeneau, Andre
    Ellis, Megan
    Fishkin, Nathan
    Harvey, Lauren
    Johnson, Holly
    Kovtun, Yelena
    Maloney, Erin
    Miller, Michael
    Wilhelm, Alan
    Chari, Ravi
    CANCER RESEARCH, 2014, 74 (19)
  • [40] In vitro and in vivo induction of human LoVo cells into apoptotic process by non-invasive microwave treatment:: A potentially novel approach for physical therapy of human colorectal cancer
    Maeda, K
    Maeda, T
    Qi, YL
    ONCOLOGY REPORTS, 2004, 11 (04) : 771 - 775