A half-century of neurotransmitter research: Impact on neurology and psychiatry (nobel lecture)

被引：0

作者：

Carlsson, A ^{[1
]}

机构：

[1] Gothenburg Univ, Dept Pharmacol, S-40530 Gothenburg, Sweden

来源：

CHEMBIOCHEM | 2001年 / 2卷 / 7-8期

关键词：

dopamines; neurotransmitters; nobel lecture; Parkinson's disease; signal transduction;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The debate whether electrical stimuli (the sparks) or chemical compounds (the soup) are the transmitting agents for signals in the central nervous system was finally settled with the demonstration of the role of the catecholamines. The development of a sensitive color assay allowed it to be established that dopamine is an important neurotransmitter and is concentrated in regions of the brain responsible for the control of motor behavior. These results led to the administration Of L-DOPA, a precursor of dopamine (see scheme), to treat the symptoms of Parkinson's disease.

引用

页码：484 / +

页数：17

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