The Role of Local Therapy for Oligometastatic Prostate Cancer Should We Expect a Cure?

被引:12
|
作者
Nair, Rajesh [1 ]
Lamb, Benjamin W. [1 ]
Geurts, Nicolas [1 ]
Alghazo, Omar [1 ]
Lam, Wayne [2 ]
Lawrentschuk, Nathan [1 ,3 ]
Murphy, Declan G. [1 ,4 ]
机构
[1] Peter MacCallum Canc Ctr, Div Canc Surg, 305 Grattan St, Melbourne, Vic 3000, Australia
[2] Univ Hong Kong, Dept Urol, 9-F,Knowles Bldg Pok Fu Lam Rd, Pok Fu Lam, Hong Kong, Peoples R China
[3] Univ Melbourne, Austin Hlth, Dept Surg, 145 Studley Rd, Heidelberg, Vic 3084, Australia
[4] Univ Melbourne, Dept Oncol, Sir Peter MacCallum Canc Ctr, 305 Grattan St, Melbourne, Vic 3000, Australia
关键词
Prostate cancer; Oligometastatic disease; Radical prostatectomy; Radical radiotherapy; PSMA-PET; RADICAL PROSTATECTOMY; ANDROGEN DEPRIVATION; MEMBRANE ANTIGEN; SURVIVAL; IMPACT; MEN; RADIOTHERAPY; PET; METASTASES; OUTCOMES;
D O I
10.1016/j.ucl.2017.07.013
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The role of local treatment in oligometastatic prostate cancer remains contentious. Treatment of the prostate in metastatic disease may confer benefit, but prospective data are lacking. With improvements in treatments, aggressive strategies directed at metastases have increasingly become of clinical interest. Current evidence suggests that good local control can be achieved; however, further data are required to determine overall cancer outcomes. This article evaluates the evidence available and considers whether local treatment of oligometastatic disease is a feasible, safe, and positive strategy in this disease cohort. Cure should not be expected, although prolonged disease and treatment-free survival may be observed.
引用
收藏
页码:623 / 633
页数:11
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