Reaction kinetics determination based on microfluidic technology

Microfluidic technology has been successfully applied to determine the reaction kinetics relying on its great characteristics including narrow residence time distribution, fast mixing, high mass and heat transfer rates and very low consumption of materials. In this review, the recent progresses about the reaction kinetics measured in microreactors are comprehensively organized, and the kinetic modeling thoughts, determination methods and essential kinetic regularities contained in these studies are summarized according to the reaction types involving nitration, oxidation, hydrogenation, photochemical reaction, polymerization and other reactions. Besides, the significant advances in the innovation of microplatform are also covered. The novel reactor configuration methods were established mainly to achieve rapid and efficient data collection and analysis. Finally, the advantages of microfluidic technology for the kinetic measurement are summarized, and a perspective for the future development is provided. (C) 2021 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All rights reserved.