An expeditious synthesis of 3-nitropropionic acid and its ethyl and methyl esters

被引：20
|
作者：
Silva, PC [1 ]
Costa, JS [1 ]
Pereira, VLP [1 ]
机构：
[1] Univ Fed Rio de Janeiro, Ctr Ciencias Saude, Lab Sintese Estereosselet Subst Bioativas, BR-21941590 Rio De Janeiro, Brazil
来源：
SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 04期
关键词：
D O I：
10.1081/SCC-100000587
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis to 3-nitropropionic acid 1 was easily accomplished, in two steps, from commercially available acrolein in 60% yield. The ethyl and methyl esters of 1 were also obtained.
引用
下载
收藏
页码：595 / 600
页数：6
相关论文
共 50 条
  • [21] 1-methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats
    Luchowski, P
    Luchowska, E
    Turski, WA
    Urbanska, EM
    NEUROSCIENCE LETTERS, 2002, 330 (01) : 49 - 52
  • [22] Autophagy, mitochondria and 3-nitropropionic acid joined in the same model
    Gonzalez-Polo, Rosa A.
    Bravo-San Pedro, Jose M.
    Gomez-Sanchez, Ruben
    Pizarro-Estrella, Elisa
    Niso-Santano, Mireia
    Fuentes, Jose M.
    BRITISH JOURNAL OF PHARMACOLOGY, 2013, 168 (01) : 60 - 62
  • [23] 3-nitropropionic acid animal model and Huntington's disease
    Borlongan, CV
    Koutouzis, TK
    Sanberg, PR
    NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 1997, 21 (03): : 289 - 293
  • [24] Inflammatory and neurochemical changes associated with 3-nitropropionic acid neurotoxicity
    Ahuja, Manuj
    Chopra, Kanwaljit
    Bishnoi, Mahendra
    TOXICOLOGY MECHANISMS AND METHODS, 2008, 18 (04) : 335 - 339
  • [25] BIOSYNTHESIS OF 3-NITROPROPIONIC ACID IN CREEPING INDIGO (INDIGOFERA SPICATA)
    CANDLISH, E
    LACROIX, LJ
    UNRAU, AM
    BIOCHEMISTRY, 1969, 8 (01) : 182 - &
  • [26] ATP DEFICITS AND NEURONAL DEGENERATION INDUCED BY 3-NITROPROPIONIC ACID
    LUDOLPH, AC
    SEELIG, M
    LUDOLPH, AG
    SABRI, MI
    SPENCER, PS
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1992, 648 : 300 - 302
  • [27] RAPID INHIBITION OF SUCCINIC-DEHYDROGENASE BY 3-NITROPROPIONIC ACID
    SABRI, MI
    AGOSTON, T
    ASKEW, J
    ALLEN, CN
    SPENCER, PS
    JOURNAL OF NEUROCHEMISTRY, 1994, 62 : S48 - S48
  • [28] Energy and glutamate dependency of 3-nitropropionic acid neurotoxicity in culture
    Fink, SL
    Ho, DY
    Sapolsky, RM
    EXPERIMENTAL NEUROLOGY, 1996, 138 (02) : 298 - 304
  • [29] Effects of chronic MPTP and 3-nitropropionic acid in nonhuman primates
    Brouillet, E
    Hantraye, P
    CURRENT OPINION IN NEUROLOGY, 1995, 8 (06) : 469 - 473
  • [30] Regulation of GSK-3β by Calpain in the 3-Nitropropionic Acid Model
    Crespo-Biel, N.
    Camins, A.
    Gutierrez-Cuesta, J.
    Melchiorri, D.
    Nicoletti, F.
    Pallas, M.
    Canudas, A. M.
    HIPPOCAMPUS, 2010, 20 (08) : 962 - 970
12345