Ruthenium-catalyzed synthesis of tri-substituted 1,3,5-triazines from alcohols and biguanides

被引：41
|
作者：
Zeng, Ming [1 ]
Wang, Tao [1 ]
Cui, Dong-Mei [1 ]
Zhang, Chen [2 ]
机构：
[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China
[2] Zhejiang Univ, Sch Pharmaceut Sci, Hangzhou 310058, Zhejiang, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2016年 / 40卷 / 10期
关键词：
BORROWING HYDROGEN METHODOLOGY; MICROWAVE-ASSISTED SYNTHESIS; SECONDARY ALCOHOLS; N-ALKYLATION; 2,4-DIAMINO-1,3,5-TRIAZINE DERIVATIVES; TRIAZINE DENDRIMERS; ORGANIC-SYNTHESIS; S-TRIAZINES; AMINES; AMINATION;
D O I：
10.1039/c6nj01620k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient ruthenium-catalyzed synthesis of tri-substituted 1,3,5-triazines from alcohols and biguanides under mild conditions has been developed. The reaction occurred in moderate to good yields and tolerated benzyl alcohol containing functionalities such as halogens. Monosubstituted to tetrasubstituted biguanidines also afforded the desired products.
引用
收藏
页码：8225 / 8228
页数：4
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