In Vitro and Ex Vivo Studies of Antioxidant Activity of Carrageenans, Sulfated Polysaccharides from Red Algae

被引:17
|
作者
Sokolova, E. V. [1 ]
Barabanova, A. O. [1 ]
Homenko, V. A. [1 ]
Solov'eva, T. F. [1 ]
Bogdanovich, R. N. [2 ]
Yermak, I. M. [1 ]
机构
[1] Russian Acad Sci, Pacific Inst Organ Biochem, Far Eastern Div, Vladivostok 690022, Russia
[2] Russian Acad Sci, Med Assoc, Far Eastern Div, Vladivostok 690022, Russia
关键词
carrageenans; red algae; superoxide anion radical; hydroxyl radical; FRAP study; BROWN;
D O I
10.1007/s10517-011-1159-5
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Antioxidant properties of structurally different sulfated polysaccharides (carrageenans) were studied in vitro and ex vivo. Ferric reducing antioxidant activity of carrageenans and their inhibitory effects on hydroxyl radicals and superoxide anion radicals were demonstrated in vitro. Activity of carrageenans depends on the polysaccharide structure. Carrageenans stimulate catalytic activity of SOD from donor erythrocyte.
引用
收藏
页码:426 / 428
页数:3
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