Autophagy triggered by ursolic acid synergistically enhances 5-fluorouracil induced cell death in HCT15 (MSI p53 mutant) colorectal cancer cells

被引：0
|
作者：
Pinto Ribeiro Xavier, C. [1 ]
Lima, C. [2 ]
Rohde, M. [3 ]
Pereira-Wilson, C. [1 ]
机构：
[1] Univ Minho, CBMA Dept Biol, Braga, Portugal
[2] Univ Minho, CITAB Dept Biol, Braga, Portugal
[3] Danish Canc Soc, Apoptosis Lab, Copenhagen, Denmark
来源：
EJC SUPPLEMENTS | 2010年 / 8卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
253
引用
收藏
页码：66 / 67
页数：2
相关论文
共 50 条
  • [31] ATF4-mediated microRNA-145/HDAC4/p53 axis affects resistance of colorectal cancer cells to 5-fluorouracil by regulating autophagy
    Lin Zhao
    Hong Chen
    QingYi Zhang
    Jin Ma
    Hao Hu
    Lu Xu
    Cancer Chemotherapy and Pharmacology, 2022, 89 : 595 - 607
  • [32] ATF4-mediated microRNA-145/HDAC4/p53 axis affects resistance of colorectal cancer cells to 5-fluorouracil by regulating autophagy
    Zhao, Lin
    Chen, Hong
    Zhang, QingYi
    Ma, Jin
    Hu, Hao
    Xu, Lu
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 89 (05) : 595 - 607
  • [33] Autophagy Regulated by Gain of Function Mutant p53 Enhances Proteasomal Inhibitor-Mediated Cell Death through Induction of ROS and ERK in Lung Cancer Cells
    Saini, Heena
    Hakeem, Ifrah
    Mukherjee, Sudeshna
    Chowdhury, Shibasish
    Chowdhury, Rajdeep
    JOURNAL OF ONCOLOGY, 2019, 2019
  • [34] Docosahexaenoic Acid-induced Autophagy is Related to Inhibition of MTor by Reactive Oxygen Species in P53 Mutant Cancer Cells
    Lim, K.
    Shin, S.
    Jing, K.
    Kim, N.
    Jeong, S.
    Oh, H.
    Heo, J. Y.
    Park, J. I.
    Yoon, W. H.
    Hwang, B. D.
    EUROPEAN JOURNAL OF CANCER, 2012, 48 : S33 - S34
  • [35] 53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM–CHK2–P53 pathway
    Jing Yao
    Ai Huang
    Xiumei Zheng
    Tao Liu
    Zhenyu Lin
    Sheng Zhang
    Qin Yang
    Tao Zhang
    Hong Ma
    Journal of Cancer Research and Clinical Oncology, 2017, 143 : 419 - 431
  • [36] β-Elemene Reverses the Resistance of p53-Deficient Colorectal Cancer Cells to 5-Fluorouracil by Inducing Pro-death Autophagy and Cyclin D3-Dependent Cycle Arrest
    Zhang, Ruonan
    Pan, Ting
    Xiang, Yu
    Zhang, Mingming
    Feng, Jiao
    Liu, Shuiping
    Duan, Ting
    Chen, Peng
    Zhai, Bingtao
    Chen, Xiaying
    Wang, Wengang
    Chen, Bi
    Han, Xuemeng
    Chen, Liuxi
    Yan, Lili
    Jin, Ting
    Liu, Ying
    Li, Guohua
    Huang, Xingxing
    Zhang, Wenzheng
    Sun, Yitian
    Li, Qiujie
    Zhang, Qin
    Zhuo, Lvjia
    Xie, Tian
    Wu, Qibiao
    Sui, Xinbing
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 8
  • [37] p53 Enhances Artemisia annua L. Polyphenols-Induced Cell Death Through Upregulation of p53-Dependent Targets and Cleavage of PARP1 and Lamin A/C in HCT116 Colorectal Cancer Cells
    Jung, Eun Joo
    Lee, Won Sup
    Paramanantham, Anjugam
    Kim, Hye Jung
    Shin, Sung Chul
    Kim, Gon Sup
    Jung, Jin-Myung
    Ryu, Chung Ho
    Hong, Soon Chan
    Chung, Ky Hyun
    Kim, Choong Won
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (23) : 1 - 17
  • [38] 5-fluorouracil(5-FU)-induced apoptosis in human gastric cancer cell lines; Role of P53, P21/Waf1
    Osaki, M
    Tatebe, S
    Goto, A
    Shomori, K
    Adachi, H
    Ito, H
    RECENT ADVANCES IN GASTROENTEROLOGICAL CARCINOGENESIS I, 1996, : 433 - 437
  • [39] Cisatracurium-induced proliferation impairment and death of colorectal cancer cells, HCT116 is mediated by p53 dependent intrinsic apoptotic pathway in vitro
    Yabasin, Iddrisu Baba
    Lu, ZhiLi
    Jia-Chuan, Yu
    Wen, Qingping
    BIOMEDICINE & PHARMACOTHERAPY, 2017, 91 : 320 - 329
  • [40] RETRACTION: JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy (Retraction of Vol 4, art no 4694, 2014)
    Sui, Xinbing
    Kong, Na
    Wang, Xian
    Fang, Yong
    Hu, Xiaotong
    Xu, Yinghua
    Chen, Wei
    Wang, Kaifeng
    Li, Da
    Jin, Wei
    Lou, Fang
    Zheng, Yu
    Hu, Hong
    Gong, Liu
    Zhou, Xiaoyun
    Pan, Hongming
    Han, Weidong
    SCIENTIFIC REPORTS, 2021, 11 (01)
12345