Regional Gray Matter Density Associated with Cognitive Reflectivity-Impulsivity: Evidence from Voxel-Based Morphometry

被引：3

作者：

Yokoyama, Ryoichi ^{[1
,2
]}

Nozawa, Takayuki ^{[3
]}

Takeuchi, Hikaru ^{[4
]}

Taki, Yasuyuki ^{[4
,5
,6
]}

Sekiguchi, Atsushi ^{[1
,5
]}

Nouchi, Rui ^{[7
]}

Kotozaki, Yuka ^{[3
]}

Nakagawa, Seishu ^{[1
]}

Miyauchi, Carlos Makoto ^{[1
,8
,9
]}

Iizuka, Kunio ^{[1
]}

Shinada, Takamitsu ^{[1
]}

Yamamoto, Yuki ^{[1
]}

Hanawa, Sugiko ^{[1
]}

Araki, Tsuyoshi ^{[3
]}

Hashizume, Hiroshi ^{[4
]}

Kunitoki, Keiko ^{[10
]}

Hanihara, Mayu ^{[10
]}

Sassa, Yuko ^{[4
]}

Kawashima, Ryuta ^{[1
,3
,4
]}

机构：

[1] Tohoku Univ, Inst Dev Aging & Canc, Dept Funct Brain Imaging, Sendai, Miyagi 980, Japan

[2] Japan Soc Promot Sci, Tokyo, Japan

[3] Tohoku Univ, Inst Dev Aging & Canc, Smart Ageing Int Res Ctr, Sendai, Miyagi 980, Japan

[4] Tohoku Univ, Inst Dev Aging & Canc, Div Dev Cognit Neurosci, Sendai, Miyagi 980, Japan

[5] Tohoku Univ, Tohoku Med Megabank Org, Dept Community Med Supports, Div Med Neuroimaging, Sendai, Miyagi 980, Japan

[6] Tohoku Univ, Inst Dev Aging & Canc, Dept Nucl Med & Radiol, Sendai, Miyagi 980, Japan

[7] Tohoku Univ, Int Res Inst Disaster Sci, Human & Social Response Res Div, Sendai, Miyagi 980, Japan

[8] Univ Tokyo, Grad Sch Law, Bunkyo Ku, Tokyo, Japan

[9] Univ Tokyo, Grad Sch Polit, Bunkyo Ku, Tokyo, Japan

[10] Tohoku Univ, Fac Med, Sendai, Miyagi 980, Japan

来源：

PLOS ONE | 2015年 / 10卷 / 03期

基金：

日本学术振兴会;

关键词：

DECISION-MAKING; PREFRONTAL CORTEX; TEMPERAMENT; ACCOUNTS; DISTINCT; NUCLEUS; VOLUME;

D O I：

10.1371/journal.pone.0122666

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

When faced with a problem or choice, humans can use two different strategies: "cognitive reflectivity," which involves slow responses and fewer mistakes, or " cognitive impulsivity,"which comprises of quick responses and more mistakes. Different individuals use these two strategies differently. To our knowledge, no study has directly investigated the brain regions involved in reflectivity-impulsivity; therefore, this study focused on associations between these cognitive strategies and the gray matter structure of several brain regions. In order to accomplish this, we enrolled 776 healthy, right-handed individuals (432 men and 344 women; 20.7 +/- 1.8 years) and used voxel-based morphometry with administration of a cognitive reflectivity-impulsivity questionnaire. We found that high cognitive reflectivity was associated with greater regional gray matter density in the ventral medial prefrontal cortex. Our finding suggests that this area plays an important role in defining an individual's trait associated with reflectivity and impulsivity.

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页数：12

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