Testicular germ cell tumors: molecular understanding and clinical implications

被引：21
|
作者：
Lutzker, SG [1 ]
Barnard, NJ [1 ]
机构：
[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Canc Inst New Jersey, New Brunswick, NJ 08901 USA
来源：
MOLECULAR MEDICINE TODAY | 1998年 / 4卷 / 09期
关键词：
D O I：
10.1016/S1357-4310(98)01329-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
It was recognized in the 1960s that testicular germ cell tumors were curable with chemotherapeutic drugs, Since that time, newer drugs including cisplatin have increased the cure rate of these tumors to over 80%, even in patients with metastatic disease. Germ cell tumors also exhibit a unique biology and genetics that distinguish them from other solid tumors and might contribute to their routine curability.
引用
收藏
页码：404 / 411
页数：8
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