The prognostic value of interim positron emission tomography scans combined with immunohistochemical data in diffuse large B-cell lymphoma

被引:0
|
作者
Fields, Paul A. [1 ]
Mikhaeel, George [2 ]
Hutchings, Martin [2 ]
van der Walt, Jon [3 ]
Nunan, Tom [4 ]
Schey, Steve A. [1 ]
机构
[1] Guys & St Thomas Hosp, Dept Haematol, London, England
[2] Guys & St Thomas Hosp, Dept Clin Oncol, London, England
[3] Guys & St Thomas Hosp, Pathol, London, England
[4] Guys & St Thomas Hosp, Clin PET Ctr, London, England
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The treatment of hematologic malignancies is moving towards risk-stratified directed therapy, whereby treatment is based on the disease's biological characteristics and response to treatment. We investigated whether BCL2 and BCL6 status could add to the prognostic information yielded by an interim positron emission tomography (PET) scan in the ability to predict outcome. Negative interim scans and BCL2-negative status correlated with continuing remission (p<0.005) at a median follow up of 24 months.
引用
收藏
页码:1711 / +
页数:3
相关论文
共 50 条
  • [41] Interim positron emission tomography scans in diffuse large B-cell lymphoma: an independent expert nuclear medicine evaluation of the Eastern Cooperative Oncology Group E3404 study
    Horning, Sandra J.
    Juweid, Malik E.
    Schoeder, Heiko
    Wiseman, Gregory
    McMillan, Alex
    Swinnen, Lode J.
    Advani, Ranjana
    Gascoyne, Randy
    Quon, Andrew
    BLOOD, 2010, 115 (04) : 775 - 777
  • [42] Improved prediction of chemoresistance in patients with diffuse large B-cell lymphoma through a new interim positron emission tomography-computed tomography evaluation model
    Xie, Wei
    Liu, Meng-Ke
    Jiang, Xu-Feng
    Gao, Xiao-Dong
    Li, Biao
    Wang, Li
    Zhao, Wei-Li
    ACTA ONCOLOGICA, 2021, 60 (06) : 735 - 743
  • [43] Mixed Response in Interim Positron Emission Tomography/Computed Tomography Leads to Detection of a Gastrointestinal Stromal Tumor in a Patient With Mediastinal Diffuse Large B-Cell Lymphoma
    Rehmsmeier, Cord
    Kessler, Torsten
    Koschmieder, Steffen
    Ross, Matthias
    Weckesser, Matthias
    Wessling, Johannes
    Koehler, Gabriele
    Berdel, Wolfgang E.
    JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (14) : E215 - E217
  • [44] Prognostic value of interim 18F-FDG PET/CT in diffuse large B-cell lymphoma
    Zhitao Ying
    Xuejuan Wang
    Yuqin Song
    Wen Zheng
    Xiaopei Wang
    Yan Xie
    Ningjing Lin
    Meifeng Tu
    Lingyan Ping
    Weiping Liu
    Lijuan Deng
    Chen Zhang
    Zhi Yang
    Jun Zhu
    Chinese Journal of Cancer Research, 2013, 25 (01) : 95 - 101
  • [45] Prognostic value of interim 18F-FDG PET/CT in diffuse large B-cell lymphoma
    Ying, Zhitao
    Wang, Xuejuan
    Song, Yuqin
    Zheng, Wen
    Wang, Xiaopei
    Xie, Yan
    Lin, Ningjing
    Tu, Meifeng
    Ping, Lingyan
    Liu, Weiping
    Deng, Lijuan
    Zhang, Chen
    Yang, Zhi
    Zhu, Jun
    CHINESE JOURNAL OF CANCER RESEARCH, 2013, 25 (01) : 95 - 101
  • [46] Interim FDG PET/CT as a prognostic factor in diffuse large B-cell lymphoma
    Fuertes, Silvia
    Setoain, Xavier
    Lopez-Guillermo, Armando
    Carrasco, Josep-Lluis
    Rodriguez, Sonia
    Rovira, Jordina
    Pons, Francesca
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 (04) : 496 - 504
  • [47] Interim FDG PET/CT as a prognostic factor in diffuse large B-cell lymphoma
    Silvia Fuertes
    Xavier Setoain
    Armando Lopez-Guillermo
    Josep-Lluis Carrasco
    Sonia Rodríguez
    Jordina Rovira
    Francesca Pons
    European Journal of Nuclear Medicine and Molecular Imaging, 2013, 40 : 496 - 504
  • [48] Dynamic model for risk assessment in diffuse large B-cell lymphoma based on positron emission tomography scanning
    Schmitz, C.
    Huettmann, A.
    Mueller, S. P.
    Hanoun, M.
    Boellaard, R.
    Brinkmann, M.
    Joeckel, K. -H.
    Duehrsen, U.
    Rekowski, J.
    ONCOLOGY RESEARCH AND TREATMENT, 2019, 42 : 67 - 67
  • [49] THE PROGNOSTIC VALUE OF INTERIM POSITRON EMISSION TOMOGRAPHY BASED ON THE DEAUVILLE 5-POINT CRITERIA AFTER 3 OR 4 CYCLES OF RITUXIMAB PLUS CHEMOTHERAPY IN NEWLY DIAGNOSED DIFFUSE LARGE B-CELL LYMPHOMA
    Kwak, J. Y.
    Yim, S. K.
    Yhim, H. Y.
    Han, Y. H.
    Jeon, S. Y.
    Lee, N. R.
    Song, E. K.
    Kim, H. S.
    Sohn, M. H.
    Yim, C. Y.
    HAEMATOLOGICA, 2012, 97 : 97 - 97
  • [50] Prognostic evaluation of immunohistochemical profiles in diffuse large B-cell lymphoma: a Chinese study
    Chen, Zi
    Du, Zunguo
    Chen, Jieqing
    Chen, Zhongqing
    Bao, Yun
    Tang, Feng
    MEDICAL ONCOLOGY, 2011, 28 (01) : 241 - 248