Microfluidic glass chips with an integrated nanospray emitter for coupling to a mass spectrometer

被引：88
|
作者：
Hoffmann, Peter
Haeusig, Ulrich
Schulze, Philipp
Belder, Detlev [1 ]
机构：
[1] Univ Regensburg, Inst Analyt Chem Chemo & Biosensor, D-93040 Regensburg, Germany
[2] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 26期
关键词：
electrophoresis; lab-on-a-chip; mass spectrometry; microfluidics; nanospray;
D O I：
10.1002/anie.200605152
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) A coupling coup: A novel microfluidic chip with an integrated nanospray emitter enables the first dead-volume-free coupling of glass-chip laboratories with mass spectrometry. An electrophoretic version of the system may be suitable for the separation and analysis of drugs, for example, and has potential for the high-throughput analysis of miniscule amounts of samples. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：4913 / 4916
页数：4
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