Quality Control of Mitochondrial Proteostasis

被引：169

作者：

Baker, Michael J. ^{[1
]}

Tatsuta, Takashi ^{[1
]}

Langer, Thomas ^{[1
,2
]}

机构：

[1] Univ Cologne, Inst Genet, Cologne Excellence Cluster Cellular Stress Respon, Ctr Mol Med CMMC, D-50674 Cologne, Germany

[2] Max Planck Inst Biol Aging, D-50931 Cologne, Germany

来源：

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY | 2011年 / 3卷 / 07期

基金：

欧洲研究理事会;

关键词：

M-AAA PROTEASE; HEREDITARY SPASTIC PARAPLEGIA; YEAST SACCHAROMYCES-CEREVISIAE; ATP-DEPENDENT PROTEASE; CYTOCHROME-C RELEASE; ABC-TRANSPORTER MDL1; HEAT-SHOCK-PROTEIN; LON PROTEASE; NEURODEGENERATIVE DISEASES; MEMBRANE-PROTEINS;

D O I：

10.1101/cshperspect.a007559

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A decline in mitochondrial activity has been associated with aging and is a hallmark of many neurological diseases. Surveillance mechanisms acting at the molecular, organellar, and cellular level monitor mitochondrial integrity and ensure the maintenance of mitochondrial proteostasis. Here we will review the central role of mitochondrial chaperones and proteases, the cytosolic ubiquitin-proteasome system, and the mitochondrial unfolded response in this interconnected quality control network, highlighting the dual function of some proteases in protein quality control within the organelle and for the regulation of mitochondrial fusion and mitophagy.

引用

页码：1 / 19

页数：19

共 50 条

[1] Mitochondrial Quality Control and Cellular Proteostasis: Two Sides of the Same Coin
Quiles, Justin M.
Gustafsson, Asa B.
[J]. FRONTIERS IN PHYSIOLOGY, 2020, 11
[2] Mitochondrial Proteostasis in the Control of Aging and Longevity
Jensen, Martin Borch
Jasper, Heinrich
[J]. CELL METABOLISM, 2014, 20 (02) : 214 - 225
[3] Amelioration of Mitochondrial Quality Control and Proteostasis by Natural Compounds in Parkinson's Disease Models
Cho, Bongki
Kim, Taeyun
Huh, Yu-Jin
Lee, Jaemin
Lee, Yun-Il
[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (20)
[4] Special Issue: Proteostasis and Protein Quality Control
Buchner, Johannes
[J]. JOURNAL OF MOLECULAR BIOLOGY, 2024, 436 (14)
[5] Mitochondrial dynamics and mitochondrial quality control
Ni, Hong-Min
Williams, Jessica A.
Ding, Wen-Xing
[J]. REDOX BIOLOGY, 2015, 4 : 6 - 13
[6] Quality control mechanisms of protein biogenesis: proteostasis dies hard
Bergmann, Timothy Jan
Pisoni, Giorgia Brambilla
Molinari, Maurizio
[J]. AIMS BIOPHYSICS, 2016, 3 (04): : 456 - 478
[7] Alteration of mitochondrial proteostasis in Costello syndrome
Lacombe, Didier
Dard, Laetitia
Rodrigue, Rossignol
[J]. EUROPEAN JOURNAL OF HUMAN GENETICS, 2023, 31 : 25 - 26
[8] A role for mitochondrial DNA in cellular proteostasis
Caroline Barranco
[J]. Nature Reviews Genetics, 2021, 22 : 690 - 690
[9] A role for mitochondrial DNA in cellular proteostasis
Barranco, Caroline
[J]. NATURE REVIEWS GENETICS, 2021, 22 (11) : 690 - 690
[10] MitoCPR: Meticulous Monitoring of Mitochondrial Proteostasis
Desai, Radha
Campanella, Michelangelo
[J]. MOLECULAR CELL, 2018, 71 (01) : 8 - 9

← 1 2 3 4 5 →