Assessing cerebellar neurometabolic biomarkers by in vivo magnetic resonance spectroscopy in a transgenic mouse model of Machado-Joseph disease

被引：0
|
作者：
Miranda, C. O. [1 ,2 ]
Nobre, R. J. [1 ,2 ]
Paiva, V. H. [2 ,3 ]
Castelhano, J. [4 ,5 ,6 ]
Petrella, L. [4 ,5 ,6 ]
Sereno, J. [4 ,5 ,6 ]
Castelo-Branco, M. [4 ,5 ,6 ]
Pereira de Almeida, L. [1 ,7 ]
机构：
[1] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, Fac Med, Rua Larga,Polo 1,1 Andar, P-3004504 Coimbra, Portugal
[2] Univ Coimbra, Inst Interdisciplinary Res, Casa Costa Alemao Polo 2, P-3030789 Coimbra, Portugal
[3] Univ Coimbra, Dept Life Sci, Marine & Environm Sci Ctr, P-3004517 Coimbra, Portugal
[4] Coimbra Inst Biomed Imaging & Translat Res, Edificio ICNAS,Polo 3, P-3000548 Coimbra, Portugal
[5] Univ Coimbra, Inst Nucl Sci Appl Hlth, Polo 3, P-3000548 Coimbra, Portugal
[6] Univ Coimbra, Inst Biomed Imaging & Life Sci IBILI, Polo 3, P-3000548 Coimbra, Portugal
[7] Univ Coimbra, Fac Pharm, Polo 3, P-3000548 Coimbra, Portugal
来源：
HUMAN GENE THERAPY | 2018年 / 29卷 / 12期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
P211
引用
收藏
页码：A90 / A90
页数：1
相关论文
共 50 条
  • [21] Magnetic resonance imaging demonstrates differential atrophy of pontine base and tegmentum in Machado-Joseph disease
    Yoshizawa, T
    Watanabe, M
    Frusho, K
    Shoji, S
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2003, 215 (1-2) : 45 - 50
  • [22] Brain single-photon emission computed tomography and magnetic resonance imaging in Machado-Joseph disease
    Etchebehere, ECSC
    Cendes, F
    Lopes-Cendes, I
    Pereira, JA
    Lima, MCL
    Sansana, CR
    Silva, CAM
    Camargo, MFAG
    Santos, AO
    Ramos, CD
    Camargo, EE
    ARCHIVES OF NEUROLOGY, 2001, 58 (08) : 1257 - 1263
  • [23] Region-Specific Changes in the Expression of Hsp70 in the Central Nervous System of a Transgenic Mouse Model of Machado-Joseph Disease
    Cruto, Teresa
    Teixeira-Castro, Andreia
    Silva-Fernandes, Anabela
    Costa, Maria do Carmo
    Duarte-Silva, Sara
    Maciel, Patricia
    NEUROLOGY, 2009, 72 (11) : A394 - A394
  • [24] Motor uncoordination and neuropathology in a transgenic mouse model of Machado-Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products
    Silva-Fernandes, Anabela
    Costa, Maria do Carmo
    Duarte-Silva, Sara
    Oliveira, Pedro
    Botelho, Claudia M.
    Martins, Luis
    Mariz, Jose Antonio
    Ferreira, Tiago
    Ribeiro, Filipa
    Correia-Neves, Margarida
    Costa, Cristina
    Maciel, Patricia
    NEUROBIOLOGY OF DISEASE, 2010, 40 (01) : 163 - 176
  • [25] Antagonism of adenosine A2A receptors delays neurodegeneration in a lentiviral mouse model of Machado-Joseph disease
    Goncalves, Nelio Da Mota
    Simoes, Ana T.
    Cunha, Rodrigo A.
    De Almeida, Luis Pereira
    PURINERGIC SIGNALLING, 2010, 6 : 135 - 135
  • [26] In vivo, longitudinal, 1H Magnetic Resonance Spectroscopy in a transgenic mouse model of Huntington's Disease
    Page, RA
    Ordidge, RJ
    Cady, EB
    Thornton, JS
    Bates, GP
    Davie, CA
    MOVEMENT DISORDERS, 2002, 17 : S176 - S177
  • [27] Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease
    Silva-Fernandes, Anabela
    Duarte-Silva, Sara
    Neves-Carvalho, Andreia
    Amorim, Marina
    Soares-Cunha, Carina
    Oliveira, Pedro
    Thirstrup, Kenneth
    Teixeira-Castro, Andreia
    Maciel, Patricia
    NEUROTHERAPEUTICS, 2014, 11 (02) : 433 - 449
  • [28] Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease
    Anabela Silva-Fernandes
    Sara Duarte-Silva
    Andreia Neves-Carvalho
    Marina Amorim
    Carina Soares-Cunha
    Pedro Oliveira
    Kenneth Thirstrup
    Andreia Teixeira-Castro
    Patrícia Maciel
    Neurotherapeutics, 2014, 11 : 433 - 449
  • [29] IN VIVO PROTON MAGNETIC RESONANCE SPECTROSCOPY IN A TRANSGENIC RAT MODEL OF ALZHEIMER'S DISEASE
    Nilsen, L. H.
    Melo, T. M.
    Saether, O.
    Witter, M. P.
    Sonnewald, U.
    JOURNAL OF NEUROCHEMISTRY, 2011, 118 : 199 - 199
  • [30] A necropsied case of Machado-Joseph disease with a hyperintense signal of transverse pontine fibres on long TR sequences of magnetic resonance images
    Imon, Y
    Katayama, S
    Kawakami, H
    Murata, Y
    Oka, M
    Nakamura, S
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1998, 64 (01): : 140 - 141
12345