Evaluation of platelet activation and platelet-neutrophil aggregates in Thoroughbreds undergoing near-maximal treadmill exercise

被引:1
|
作者
Weiss, DJ [1 ]
Evanson, OA
Fagliari, JJ
Valberg, S
机构
[1] Univ Minnesota, Coll Vet Med, Dept Vet Pathobiol, St Paul, MN 55108 USA
[2] Univ Minnesota, Coll Vet Med, Dept Clin & Populat Sci, St Paul, MN 55108 USA
关键词
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Objectives-To determine whether platelets become activated and form platelet-neutrophil aggregates during near-maximal treadmill exercise in horses. Animals-4 Thoroughbreds. Procedure-Horses were subjected to 4 standardized exercise tests on a treadmill, and blood samples were collected before exercise, at treadmill speed of 12 m/s, and 5 minutes after exercise. Flow cytometric techniques were used to identify activated platelets, and flow cytometric and microscopic techniques were used to identify platelet-neutrophil aggregates. Results-Platelet-neutrophil aggregates increased from 2.8 +/- 0.4% at rest to 17.2 +/- 1.1% and 14.7 +/- 1.6% during and after exercise, respectively. Platelet activation was not detected during or after exercise. Conclusions-Platelet-neutrophil aggregates consistently form during strenuous exercise in horses.
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收藏
页码:393 / 396
页数:4
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