HECK-MIZOROKI REACTION OF 4-IODO-1H-PYRAZOLES

被引：9
|
作者：
Usami, Yoshihide [1 ]
Ichikawa, Hayato [1 ]
Harusawa, Shinya [1 ]
机构：
[1] Osaka Univ Pharmaceut Sci, Lab Pharmaceut Organ Chem, Osaka 5691094, Japan
来源：
HETEROCYCLES | 2011年 / 83卷 / 04期
关键词：
4-Alkenyl-1H-pyrazole; Synthesis; Heck-Mizoroki Reaction; Palladium; Direct Functionalization; CROSS-COUPLING REACTION; PALLADIUM; HALIDES; ARYL;
D O I：
10.3987/COM-11-12146
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Heck-Mizoroki reaction of 1-protected-4-iodo-1H-pyrazoles with various kinds of alkenes was examined and found to yield 1-protected-4-alkenyl-1H-pyrazoles. P(OEt)(3) was a suitable ligand for the cross-coupling reaction, together with the trityl group that acted as an appropriate protecting group of 1H-pyrazole.
引用
收藏
页码：827 / 835
页数：9
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