DIFFERENTIAL METHYLATION AS A POTENTIAL BIOMARKER OF METHOTREXATE RESPONSE IN PATIENTS WITH RHEUMATOID ARTHRITIS

被引:1
|
作者
Nair, N. [1 ,2 ]
Plant, D. [1 ,2 ,3 ]
Verstappen, S. M. [1 ,2 ]
Isaacs, J. D. [4 ,5 ]
Morgan, A. W. [6 ]
Hyrich, K. L. [1 ,2 ]
Barton, A. [1 ,2 ]
Wilson, A. G. [7 ]
机构
[1] Univ Manchester, Arthrit Res UK Ctr Genet & Genom, Manchester, Lancs, England
[2] Univ Manchester, Genom & Ctr Epidemiol, Manchester, Lancs, England
[3] CMFT, NIHR Manchester Musculoskeletal BRU, Manchester, Lancs, England
[4] Newcastle Upon Tyne Hosp NHS Fdn Trust, NIHR Newcastle BRU, Newcastle Upon Tyne, Tyne & Wear, England
[5] Newcastle Univ, Newcastle Upon Tyne, Tyne & Wear, England
[6] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds, W Yorkshire, England
[7] Univ Coll Dublin, Sch Med & Med Sci, Dublin, Ireland
关键词
D O I
10.1136/annrheumdis-2017-eular.6330
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
THU0001
引用
收藏
页码:200 / 200
页数:1
相关论文
共 50 条
  • [21] Prediction of response to methotrexate in rheumatoid arthritis
    Ling, Stephanie
    Bluett, James
    Barton, Anne
    EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2018, 14 (05) : 419 - 429
  • [22] IDENTIFICATION OF POTENTIAL BIOMARKER PANELS PREDICTIVE OF NON-RESPONSE IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH METHOTREXATE: A GENE-EXPRESSION-PROFILING APPROACH
    Smith, Samantha L.
    Plant, Darren
    Sellu, James
    Hyrich, Kimme
    Barton, Anne
    Verstappen, Suzanne M. M.
    RHEUMATOLOGY, 2014, 53 : 158 - 159
  • [23] The Macrophage Reprogramming Ability of Antifolates Reveals Soluble CD14 as a Potential Biomarker for Methotrexate Response in Rheumatoid Arthritis
    Fuentelsaz-Romero, Sara
    Barrio-Alonso, Celia
    Garcia Campos, Raquel
    Torres Torresano, Monica
    Muller, Ittai B.
    Triguero-Martinez, Ana
    Nuno, Laura
    Villalba, Alejandro
    Garcia-Vicuna, Rosario
    Jansen, Gerrit
    Miranda-Carus, Maria-Eugenia
    Gonzalez-Alvaro, Isidoro
    Puig-Kroger, Amaya
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [24] Time to treatment response with abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate
    Kremer, J. M.
    Westhovens, R.
    Le Bars, M.
    Lafosse, C.
    Gaillez, C.
    Koncz, T.
    Schmidely, N.
    Dougados, M.
    Schiff, M.
    ARTHRITIS AND RHEUMATISM, 2008, 58 (09): : S308 - S308
  • [25] Calprotectin as a biomarker in rheumatoid arthritis: the potential predictive value of response to treatment
    Caproli, Alessia
    Pina, Silvia Della
    Vezzoli, Marika
    Cavazzana, Ilaria
    Airo, Paolo
    Brugnoni, Duilio
    Franceschini, Franco
    Garrafa, Emirena
    Piantoni, Silvia
    BIOANALYSIS, 2023, 15 (18)
  • [26] ATTITUDES OF RHEUMATOID ARTHRITIS PATIENTS TO METHOTREXATE
    Leonardo, N.
    Lester, S.
    Graham, M.
    Whittle, S.
    Rowett, D.
    Buchbinder, R.
    Hill, C.
    INTERNAL MEDICINE JOURNAL, 2018, 48 : 12 - 12
  • [28] PREDICTION OF RESPONSE OF METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS USING SERUM LIPIDOMICS
    Maciejewski, Mateusz
    Sands, Caroline
    Nair, Nisha
    Ling, Stephanie
    Verstappen, Suzanne
    Hyrich, Kimme
    Rams, Matura
    Barton, Anne
    Ziemek, Daniel
    Lewis, Matthew
    Plant, Darren
    RHEUMATOLOGY, 2020, 59
  • [29] Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics
    Mateusz Maciejewski
    Caroline Sands
    Nisha Nair
    Stephanie Ling
    Suzanne Verstappen
    Kimme Hyrich
    Anne Barton
    Daniel Ziemek
    Matthew R. Lewis
    Darren Plant
    Scientific Reports, 11
  • [30] Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis
    Rosario López-Rodríguez
    Aida Ferreiro-Iglesias
    Aurea Lima
    Miguel Bernardes
    Andrzej Pawlik
    Agnieszka Paradowska-Gorycka
    Jerzy Świerkot
    Ryszard Slezak
    Vita Dolžan
    Isidoro González-Álvaro
    Javier Narváez
    Rafael Cáliz
    Eva Pérez-Pampín
    Antonio Mera-Varela
    Laura Vidal-Bralo
    José Gorgonio Acuña Ochoa
    Carmen Conde
    Juan J. Gómez-Reino
    Antonio González
    Scientific Reports, 8