A potential explanation of some established major risk factors for autism

被引：13
|
作者：
James, William H. [1 ]
机构：
[1] UCL, Galton Lab, Dept Genet Evolut & Environm, London, England
来源：
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY | 2012年 / 54卷 / 04期
关键词：
PARENTAL HORMONE-LEVELS; MAMMALIAN SEX-RATIOS; ANDROGEN LEVELS; SPECTRUM DISORDERS; GROWTH-RETARDATION; DIGIT RATIO; TESTOSTERONE; BIRTH; PREGNANCY; TIME;
D O I：
10.1111/j.1469-8749.2012.04225.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
BaronCohen hypothesized that a cause of autism in infants is exposure to high concentrations of intrauterine testosterone concentrations. Some of the subsequent research on this hypothesis has focused on the possibility that the source of this testosterone is the fetus; however, this review shows that if the source is taken to be the mother, then many of the established risk factors for autism could be explained. If that were correct, it would follow that high maternally derived intrauterine androgen concentrations may be a major environmental cause of autism.
引用
收藏
页码：301 / 305
页数：5
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