Liquid chromatographic analysis of vitamin B6 in soy-based infant formula

被引：0
|
作者：
Mann, DL
Chase, GW
Eitenmiller, RR
机构：
[1] US FDA, SE Reg Lab, Atlanta, GA 30309 USA
[2] US FDA, Pacific Reg Lab NW, Bothell, WA 98021 USA
[3] Univ Georgia, Dept Food Sci & Technol, Athens, GA 30602 USA
来源：
JOURNAL OF AOAC INTERNATIONAL | 2001年 / 84卷 / 05期
关键词：
D O I：
暂无
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A liquid chromatographic (LC) method is described for determination of total vitamin B-6 in soy-based infant formula. Total vitamin B-6 is quantitated by using ion-pair LC after precolumn transformation of phosphorylated and free vitamers into pyridoxol. The limit of detection is 0.3 ng and the limit of quantitation is 1.0 ng on-column (injection volume = 100 muL). Linear response ranged from 39 to 616 ng/mL (r(2) = 0.99986). Analysis of a soy-based infant formula control fortified at 6 different concentration levels gave recoveries that averaged 104%. Assay of SRM 1846 gave results within the certified range (8.6 +/-0.086 mg/kg versus the certified value of 8.4 +/-1.0 mg/kg). The method provides a rapid and specific assay for the analysis of total vitamin B-6 in fortified soy-based infant formula.
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收藏
页码：1593 / 1599
页数：7
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