Somatostatin receptor scintigraphy of a patient with a giant invasive prolactinoma

被引：2
|
作者：
Meyer, P
Bohnen, NI
Barkan, AL
Shapiro, B
机构：
[1] Univ Michigan, Med Ctr, Dept Internal Med, Div Nucl Med, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Med Ctr, Div Endocrinol & Metab, Ann Arbor, MI USA
来源：
NUKLEARMEDIZIN | 1999年 / 38卷 / 02期
关键词：
octreotide; pituitary adenoma; prolactinoma; somatostatin;
D O I：
10.1055/s-0038-1632192
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 41-year-old with a giant prolactinoma underwent In-111 pentetreotide (Octreotide) imaging showing very intense tracer uptake in the region of the anterior skull base. In contrast, there was no significant response to Octreotide therapy. Prediction of clinical responsiveness to Octreotide therapy in patients with pituitary adenomas may depend on the presence of somatostatin receptor subtype 5. Pentetreotide does not avidly bind to this receptor subtype and therefore, cannot be used clinically to predict therapeutic Octreotide responsiveness in patients with large prolactinomas.
引用
收藏
页码：66 / 67
页数：2
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