Gut microbiota in inflammatory bowel disease: a target for therapy not to be missed

被引：6

作者：

Larussa, Tiziana ^{[1
]}

Abenavoli, Ludovico ^{[1
]}

Fabiano, Giulia ^{[1
]}

Mancuso, Maria A. ^{[1
]}

Polimeni, Natale ^{[2
]}

Dumitrascu, Dan L. ^{[3
]}

Luzza, Francesco ^{[1
]}

机构：

[1] Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa, I-88100 Catanzaro, Italy

[2] Casa Cura Policlin Madonna Consolaz, Digest Endoscopy Serv, Reggio Di Calabria, Italy

[3] Iuliu Hatieganu Univ Med & Pharm, Med Dept 2, Cluj Napoca, Romania

来源：

MINERVA GASTROENTEROLOGY | 2021年 / 67卷 / 04期

关键词：

Inflammatory bowel diseases; Microbiota; Dysbiosis; GLUTEN-FREE DIET; ULCERATIVE-COLITIS; CROHNS-DISEASE; GASTROINTESTINAL SYMPTOMS; INTESTINAL MICROBIOTA; ALTERNATIVE MEDICINE; MEDITERRANEAN DIET; CARBOHYDRATE-DIET; ESCHERICHIA-COLI; FECAL MICROBIOTA;

D O I：

10.23736/S2724-5985.21.02907-7

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

In the last years, the gut microbiota achieved great importance, since several studies demonstrated its correlation with the immune system and with the maintenance of intestinal homeostasis, as well as with the regulation of the integrity of the epithelium and the intestinal motility. An imbalance in microbial species promotes a dysbiosis, which has been associated with chronic diseases such as metabolic syndrome, inflammatory diseases, and some behavior disorders. The association with gut microbiota and dysbiosis has been demonstrated mostly in inflammatory bowel disease (IBD). Several studies investigated the application of antibiotics, prebiotics, probiotics, and fecal microbiota transplantation in the treatment strategies for IBD. In this review, we discuss the recent findings on the potential role of the gut microbiota manipulation, with particular attention to bacterial microbiota, which could be implicated for a successful IBD therapeutic approach. (Cite this article as: Larussa T, Abenavoli L, Fabiano G, Mancuso MA, Polimeni N, Dumitrascu DL, et al. Gut microbiota in inflammatory bowel disease: a target for therapy not to be missed. Minerva Gastroenterol 2021;67:357-68. DOI: 10.23736/ S2724-5985.21.02907-7)

引用

页码：357 / 368

页数：12

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