Prevalence and correlates of Alzheimer's disease and related dementias in rural Uganda: cross-sectional, population-based study

被引:29
|
作者
Mubangizi, Vincent [1 ]
Maling, Samuel [1 ]
Obua, Celestino [1 ]
Tsai, Alexander C. [1 ,2 ,3 ]
机构
[1] Mbarara Univ Sci & Technol, Mbarara, Uganda
[2] Massachusetts Gen Hosp, Boston, MA 02114 USA
[3] Harvard Med Sch, Boston, MA 02115 USA
基金
美国国家卫生研究院;
关键词
Alzheimer's disease; Dementia; Sub-Saharan Africa; Uganda; INSECURITY; AFRICA;
D O I
10.1186/s12877-020-1461-z
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background There is a paucity of data on the prevalence and correlates of Alzheimer's disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer's disease and related dementias in rural Uganda. Methods We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia. Results Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10-1.03, p<0.001), having some formal education (AOR, 0.57; 95% CI, 0.41-0.81, p = 0.001), exercise (AOR, 0.44; 95% CI, 0.27-0.72, p = 0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24-0.77, p = 0.001). Conclusions In this population-based sample of older-age adults in rural Uganda, nearly one-fifth screened positive for dementia.
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页数:7
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