Investigational antiviral drugs for the treatment of COVID-19

被引：0

作者：

Vegivinti, C. T. R. ^{[1
]}

Assi, M. ^{[2
]}

Talwani, R. ^{[3
]}

Koblizek, V ^{[4
,5
]}

Burke, K. ^{[6
]}

Temesgen, Z. ^{[7
]}

机构：

[1] Manipal Acad Higher Educ MAHE, Kasturba Med Coll, Dept Gen Med, Manipal, Karnataka, India

[2] Virginia Commonwealth Univ, Dept Internal Med, Richmond, VA USA

[3] Univ Maryland, Div Infect Dis, Baltimore, MD 21201 USA

[4] Charles Univ Prague, Univ Hosp Hradec Kralove, Prague, Czech Republic

[5] Charles Univ Prague, Fac Med, Prague, Czech Republic

[6] Wolters Kluwer, Clin Effectiveness, Indianapolis, IN USA

[7] Mayo Clin & Mayo Fdn, Div Infect Dis, Rochester, MN USA

来源：

DRUGS OF THE FUTURE | 2021年 / 46卷 / 09期

基金：

美国国家卫生研究院;

关键词：

COVID-19; SARS-CoV-2; Remdesivir; Hydroxychloroquine; Lopinavir/ritonavir; Ribavirin; Ivermectin; Favipiravir; Umifenovir; Camostat; Nafamostat Nitazoxanide; DAS-181; RESPIRATORY SYNDROME CORONAVIRUS; SIALIDASE FUSION PROTEIN; NAFAMOSTAT MESILATE; INTERFERON-THERAPY; RIBAVIRIN; INHIBITOR; DAS181; IVERMECTIN; RITONAVIR; INFECTION;

D O I：

10.1358/dof.2021.46.9.3293585

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A large number of candidate drugs are undergoing evaluation for their potential to limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Clinical trial data are slowly emerging for several of these agents. We provide a review of candidate antiviral agents registered in ClinicalTrials.gov , which have clinical efficacy data, provide the rationale for their consideration for this purpose, and summarize available data on their efficacy and safety.

引用

页码：697 / 710

页数：14

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