Incidence and risk factors for rebleeding after emergency endoscopic hemostasis for marginal ulcer bleeding

Background: Marginal ulcer bleeding is a cause of upper gastrointestinal bleeding, but the effi-cacy of emergency endoscopic hemostasis and risk factors for rebleeding have not been fully explored. The purpose of the current study was to investigate the rebleeding rate and risk fac-tors after emergency endoscopic hemostasis for marginal ulcer bleeding.Methods: We conducted a retrospective study of 105 patients who underwent emergency endo-scopic hemostasis due to marginal ulcer bleeding from January 2015 to July 2021. Patients included in this study were divided into rebleeding and non-rebleeding groups.Results: Among the 105 patients, 15.2% (16/105) patients developed rebleeding within 30 days after endoscopic hemostasis, and 87.5% of the patients had rebleeding within 7 days. The mean age of these patients was 60.3 +/- 12.3 years, and 95 of them were male. In the univariate analy-sis, an ulcer size >10 mm, a PLT count <100 x 10"9/L and an AIMS65 score >2 were risk factors for rebleeding. According to the multivariable analysis, an ulcer size >10 mm (OR: 3.715; 95% CIs: 1.060-14.250; p = 0.043) and a PLT count <100 x 10"9/L (OR: 4.480; 95% CIs: 1.099-18.908; p = 0.035) were independent risk factors for rebleeding.Conclusion: Emergency endoscopic hemostasis is an effective treatment for marginal ulcer bleeding. An ulcer size >10 mm and a PLT count <100 x 10"9/L were independent risk factors for rebleeding within 30 days after endoscopic hemostasis for marginal ulcer bleeding. (c) 2022 Elsevier Masson SAS. All rights reserved.