Reactivity of bis-vinylphosphates obtained from imide derivatives. Synthesis of 2,6-disubstituted 1,4-dihydropyridines

被引：21

作者：

Mousset, D ^{[1
]}

Gillaizeau, I ^{[1
]}

Hassan, J ^{[1
]}

Lepifre, F ^{[1
]}

Bouyssou, P ^{[1
]}

Coudert, G ^{[1
]}

机构：

[1] Univ Orleans, UMR 6005, Inst Chim Organ & Analyt, F-45067 Orleans, France

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 21期

关键词：

2,6-disubstituted 1,4-dihydropyridines; ene-carbamate; vinylphosphate; palladium coupling reaction;

D O I：

10.1016/j.tetlet.2005.03.136

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Pd-catalyzed functionalization of lactam-derived vinyl phosphates has become an important tool in the last decade for the synthesis of nitrogen-containing heterocycles. By using this method, we were able to introduce alkenyl, aryl and heteroaryl groups on bis-vinylphosphate derivatives to provide efficient access to 2,6-disubstituted 1,4-dihydropyridines. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：3703 / 3705

页数：3

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