Physiologically-based pharmacokinetic modelling in veterinary medicine.

被引：0
|
作者：
Chapel, AM
Sanders, P
机构：
来源：
REVUE DE MEDECINE VETERINAIRE | 1996年 / 147卷 / 05期
关键词：
pharmacokinetic model; physiology; veterinary; surgeon;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The physiologically-based pharmacokinetic modelling is useful in veterinary medicine. This model can predict the drug tissular concentrations for different treatments. The development of the physiologically-based pharmacokinetic models consists on three steps. The first is the model representation with a diagram and the mathematical equations who describe the different interrelationships. Then, the mathematical equations parameters must be obtain. There are physiological, physicochemical and biochemical parameters. The last step is the model validation. Some applications of the physiologically-based pharmacokinetic model are given in this review.
引用
收藏
页码：359 / 366
页数：8
相关论文
共 50 条
  • [31] Evidence based veterinary medicine.
    Arlt, S
    Heuwieser, W
    DEUTSCHE TIERARZTLICHE WOCHENSCHRIFT, 2005, 112 (04): : 146 - 148
  • [32] Pharmacokinetic Characterization to Enable Medicine Use in Pregnancy, the Potential Role of Physiologically-Based Pharmacokinetic Modeling: A Regulatory Perspective
    Cole, Susan
    Coppola, Paola
    Kerwash, Essam
    Nooney, Janet
    Lam, Siu Ping
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2020, 9 (10): : 547 - 549
  • [33] A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL FOR FLUORIDE UPTAKE BY BONE
    RAO, HV
    BELILES, RP
    WHITFORD, GM
    TURNER, CH
    REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1995, 22 (01) : 30 - 42
  • [34] Endocytosis mechanism in physiologically-based pharmacokinetic modeling of nanoparticles
    Deng, Linjing
    Liu, Hui
    Ma, Yongsheng
    Miao, Yufeng
    Fu, Xiaoli
    Deng, Qihong
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 384
  • [35] The development of a stochastic physiologically-based pharmacokinetic model for lead
    Beck, BD
    Mattuck, RL
    Bowers, TS
    Cohen, JT
    O'Flaherty, E
    SCIENCE OF THE TOTAL ENVIRONMENT, 2001, 274 (1-3) : 15 - 19
  • [36] A physiologically-based pharmacokinetic model of drug detoxification by nanoparticles
    Fallon, MS
    Varshney, M
    Dennis, DM
    Chauhan, A
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2004, 31 (05) : 381 - 400
  • [37] Physiologically-based pharmacokinetic modeling of ziprasidone in pregnant women
    Biesdorf, Carla
    Martins, Frederico
    Diniz, Andrea
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2018, 45 : S12 - S13
  • [38] A Comprehensive Framework for Physiologically-Based Pharmacokinetic Modeling in Matlab
    Stader, Felix
    Penny, Melissa A.
    Siccardi, Marco
    Marzolini, Catia
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2019, 8 (07): : 444 - 459
  • [39] Physiologically-Based Pharmacokinetic Modeling: Parameter Estimation for Cyclosporin A
    Lueshen, Eric
    Hall, Cierra
    Mosat, Andrej
    Linninger, Andreas
    21ST EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING, 2011, 29 : 1543 - 1547
  • [40] An Overview of Physiologically-Based Pharmacokinetic Models for Forensic Science
    Fairman, Kiara
    Choi, Me-Kyoung
    Gonnabathula, Pavani
    Lumen, Annie
    Worth, Andrew
    Paini, Alicia
    Li, Miao
    TOXICS, 2023, 11 (02)
12345