Inhibitors of the Src SH2 domain and Src tyrosine kinase as potential anticancer drugs

被引：0
|
作者：
Tranter, D [1 ]
机构：
[1] Univ Nottingham, Canc Res Labs, Nottingham NG7 2RD, England
来源：
DRUG DISCOVERY TODAY | 2001年 / 6卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：215 / 216
页数：2
相关论文
共 50 条
  • [41] Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk
    Wong, L
    Lieser, S
    Chie-Leon, B
    Miyashita, O
    Aubol, B
    Shaffer, J
    Onuchic, JN
    Jennings, PA
    Woods, VL
    Adams, JA
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2004, 341 (01) : 93 - 106
  • [42] The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src
    Gonfloni, S
    Williams, JC
    Hattula, K
    Weijland, A
    Wierenga, RK
    Superti-Furga, G
    [J]. EMBO JOURNAL, 1997, 16 (24): : 7261 - 7271
  • [43] Induction of osteoclast apoptosis by mutated src proteins and a src SH2 inhibitor
    Xing, L
    Schwartzberg, P
    Sawyer, T
    Varmus, HE
    Boyce, BF
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 1997, 12 : 25 - 25
  • [44] A starfish EGG SRC family tyrosine kinase associates with PLCγ-1 SH2 domains at fertilization.
    Giusti, AF
    Carroll, DJ
    Abassi, YA
    Foltz, KR
    [J]. MOLECULAR BIOLOGY OF THE CELL, 1998, 9 : 7A - 7A
  • [45] Molecular rulers: An assessment of distance and spatial relationships of Src tyrosine kinase SH2 and active site regions
    Profit, AA
    Lee, TR
    Niu, J
    Lawrence, DS
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (12) : 9446 - 9451
  • [46] Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation
    Wong, L
    Lieser, SA
    Miyashita, O
    Miller, M
    Tasken, K
    Onuchic, JN
    Adams, JA
    Woods, VL
    Jennings, PA
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2005, 351 (01) : 131 - 143
  • [47] Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions
    Groveman, Bradley R.
    Xue, Sheng
    Marin, Vedrana
    Xu, Jindong
    Ali, Mohammad K.
    Bienkiewicz, Ewa A.
    Yu, Xian-Min
    [J]. FEBS JOURNAL, 2011, 278 (04) : 643 - 653
  • [48] Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand
    Plummer, MS
    Holland, DR
    Shahripour, A
    Lunney, EA
    Fergus, JH
    Marks, JS
    McConnell, P
    Mueller, WT
    Sawyer, TK
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (23) : 3719 - 3725
  • [49] The formation of a covalent complex between a dipeptide ligand and the src SH2 domain
    Alligood, KJ
    Charifson, PS
    Crosby, R
    Consler, TG
    Feldman, PL
    Gampe, RT
    Gilmer, TM
    Jordan, SR
    Milstead, MW
    Mohr, C
    Peel, MR
    Rocque, W
    Rodriguez, M
    Rusnak, DW
    Shewchuk, LM
    Sternbach, DD
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (10) : 1189 - 1194
  • [50] Design of peptidomimetic ligands for the pp60(src) SH2 domain
    Plummer, MS
    Lunney, EA
    Para, KS
    Shahripour, A
    Stankovic, CJ
    Humblet, C
    Fergus, JH
    Marks, JS
    Herrera, R
    Hubbell, S
    Saltiel, A
    Sawyer, TK
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 1997, 5 (01) : 41 - 47
12345