ANTIMICROBIAL AND ANTI-PATHOGENIC ACTIVITY EVALUATION OF SOME 2-(TRIMETHOXYPHENYL)-4-AR1-5-R2-THIAZOLES

被引：0

作者：

Araniciu, Catalin ^{[1
]}

Oniga, Smaranda ^{[1
]}

Oniga, Ovidiu ^{[1
]}

Palage, Mariana ^{[1
]}

Chifiriuc, Mariana-Carmen ^{[2
]}

Marutescu, Luminita ^{[2
]}

机构：

[1] Iuliu Hatieganu Univ Med & Pharm, Fac Pharm, Cluj Napoca 400010, Romania

[2] Univ Bucharest, Dept Microbiol, Fac Biol, Bucharest 60101, Romania

来源：

FARMACIA | 2015年 / 63卷 / 01期

关键词：

antimicrobial; anti-biofilm; aryl-thiazoles; THIOUREA DERIVATIVES; AGENTS; MECHANISMS;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A series of 9 compounds with a 2-(3,4,5-trimethoxyphenyl) thiazolyl structure were tested in order to determine their antimicrobial potential, using a qualitative screening method followed by a quantitative assay in order to determine the antimicrobial activity. The anti-pathogenic activity was investigated by the study of anti-biofilm activity of the obtained molecules. The tested substances showed a low to moderate microbicidal activity, but a good anti-biofilm activity.

引用

页码：40 / 45

页数：6

共 50 条

[41] Synthesis and Antimicrobial Activity of Some [1,2,4]-Triazole Derivatives
Patil, Bhimagouda S.
Krishnamurthy, G.
Shashikumar, N. D.
Lokesh, M. R.
Naik, H. S. Bhojya
JOURNAL OF CHEMISTRY, 2013, 2013
[42] Synthesis and antimicrobial activity of some new 2-(3′-phenoxy phenyl)-3-aryl-5-methyl-4-thiazolidinones
Solankee, A
Patel, J
Kapadia, K
Thakor, I
Upadhyay, K
ASIAN JOURNAL OF CHEMISTRY, 2002, 14 (02) : 718 - 722
[43] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME 2-AMINO-4-ARYL-5-CHROMANYLAZOTHIAZOLES
AHLUWALIA, VK
SINGH, RP
SINGH, RP
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1987, 26 (03): : 287 - 289
[44] Synthesis and antimicrobial evaluation of novel ethyl 2-(2-(4-substituted)acetamido)-4-subtituted-thiazole-5-carboxylate derivatives
Pawar, Chandrakant D.
Sarkate, Aniket P.
Karnik, Kshipra S.
Bahekar, Sushilkumar S.
Pansare, Dattatraya N.
Shelke, Rohini N.
Jawale, Chetan S.
Shinde, Devanand B.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (15) : 3525 - 3528
[45] ANTIMICROBIAL ACTIVITY EVALUATION OF 5,7,2',5'-TETRAACETOXI-4-PHENILCOUMARIN
DEARAUJO, CC
PAULA, MD
MAIA, RF
LIMA, ED
REVISTA DE MICROBIOLOGIA, 1988, 19 (02): : 177 - 179
[46] Synthesis and antimicrobial activity of some 2-(2-oxobenzothiazole-3-yl)-1-arylethanone derivatives
Simsek, R
Altas, Y
Safak, C
Abbasoglu, U
Ozcelik, B
FARMACO, 1995, 50 (12): : 893 - 894
[47] Dimethyl 2-{[2-(2-Methoxy-1-methoxycarbonyl-2-oxoethyl)-4,5,7-trimethoxy-3-(2,4,5-trimethoxyphenyl)-2,3-dihydro-1H-inden-1-yl]methyl}malonate
Boichenko, Maksim A.
Chagarovskiy, Alexey O.
Rybakov, Victor B.
Trushkov, Igor, V
Ivanova, Olga A.
MOLBANK, 2020, 2020 (01)
[48] Synthesis and biological evaluation of novel 2-(1H-imidazol-2-ylmethylidene)hydrazinyl-1,3-thiazoles as potential antimicrobial agents
Laczkowski, Krzysztof Z.
Jachowicz, Katarzyna
Misiura, Konrad
Biernasiuk, Anna
Malm, Anna
HETEROCYCLIC COMMUNICATIONS, 2015, 21 (02) : 109 - 114
[49] Synthesis and Antimicrobial Evaluation of Some Novel 2-(4-Chlorophenylimino) thiazolidin-4-one Derivatives
B'Bhatt, H.
Sharma, S.
JOURNAL OF THE KOREAN CHEMICAL SOCIETY-DAEHAN HWAHAK HOE JEE, 2012, 56 (03): : 341 - 347
[50] Synthesis and Anti-TMV activity of 2-[5-(3,4,5-trimethoxyphenyl)-1,3,4-thiadiazole-2-ylthiomethyl]-1-(2,3,4-trimethoxy)phenyl ketoxime ether derivativies
Xue, Wei
Song, Bao-An
Wang, Hua
He, Wei
Yang, Song
Jin, Lin-Hong
Hu, De-Yu
Liu, Gang
Lu, Ping
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2006, 26 (05) : 702 - 706

← 1 2 3 4 5 →