ANTIMICROBIAL AND ANTI-PATHOGENIC ACTIVITY EVALUATION OF SOME 2-(TRIMETHOXYPHENYL)-4-AR1-5-R2-THIAZOLES

被引：0

作者：

Araniciu, Catalin ^{[1
]}

Oniga, Smaranda ^{[1
]}

Oniga, Ovidiu ^{[1
]}

Palage, Mariana ^{[1
]}

Chifiriuc, Mariana-Carmen ^{[2
]}

Marutescu, Luminita ^{[2
]}

机构：

[1] Iuliu Hatieganu Univ Med & Pharm, Fac Pharm, Cluj Napoca 400010, Romania

[2] Univ Bucharest, Dept Microbiol, Fac Biol, Bucharest 60101, Romania

来源：

FARMACIA | 2015年 / 63卷 / 01期

关键词：

antimicrobial; anti-biofilm; aryl-thiazoles; THIOUREA DERIVATIVES; AGENTS; MECHANISMS;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A series of 9 compounds with a 2-(3,4,5-trimethoxyphenyl) thiazolyl structure were tested in order to determine their antimicrobial potential, using a qualitative screening method followed by a quantitative assay in order to determine the antimicrobial activity. The anti-pathogenic activity was investigated by the study of anti-biofilm activity of the obtained molecules. The tested substances showed a low to moderate microbicidal activity, but a good anti-biofilm activity.

引用

页码：40 / 45

页数：6

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