Elevated anti-sulfatide antibodies in Guillain-Barre syndrome in T cell depleted at end-stage AIDS

被引：9
|
作者：
Souayah, Nizar [1 ]
Mian, Nimer F. [1 ]
Gu, Yajuan [1 ]
Ilyas, Amjad A. [1 ]
机构：
[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Neurol & Neurosci, Newark, NJ 07103 USA
来源：
JOURNAL OF NEUROIMMUNOLOGY | 2007年 / 188卷 / 1-2期
关键词：
AIDS; HIV; Guillain-Barre syndrome; antibody; sulfatide;
D O I：
10.1016/j.jneuroim.2007.05.020
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A 38-year-old man developed the Guillain-Barre' syndrome (GBS) associated with untreated end-stage AIDS and CD4+ lymphocyte count of 3 cells/mm (3). The patient had serum high titer anti-sulfatide antibodies and responded well to infusion of immunoglobulin. The data suggest that elevated levels of anti-sulfatide antibodies may play a role in the pathogenesis of GBS in this patient, although a direct neurotropic effect of HIV virus cannot be excluded. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码：143 / 145
页数：3
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